In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has
shown rapid progress and widespread use in recent years—in multidisciplinary treatment …

Endocrine complications are highly prevalent in childhood cancer survivors. Approximately
50% of survivors will experience at least one hormonal disorder over the course of their …

Purpose There are sparse data defining the dose response of radiation therapy (RT) to the
hypothalamus and pituitary in pediatric and young adult patients with brain tumors. We …

While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

Precision radiotherapy, which accurately delivers the dose on a tumor and confers little or no
irradiation to the surrounding normal tissue and organs, results in maximum tumor control …

Proton beam therapy is a highly conformal form of radiation therapy, which currently
represents an important therapeutic component in multidisciplinary management in …

Endocrine disorders in survivors of childhood, adolescent, and young adult (CAYA) cancers
are associated with substantial adverse physical and psychosocial effects. To improve …

Background Recurrent pediatric medulloblastoma and ependymoma have a grim prognosis.
We report a first-in-human, phase I study of intraventricular infusions of ex vivo expanded …

Endocrine complications are frequently observed in childhood cancer survivors (CCS). One
of two CCS will experience at least one endocrine complication during the course of his/her …

The population of adult survivors of childhood cancer continues to grow as survival rates
improve. Although it is well established that these survivors experience various …