The Fanconi anemia pathway is a key pathway involved in the repair of deoxyribonucleic
acidinterstrand crosslinking damage, which chiefly includes the following four modules …

Premature ovarian insufficiency (POI) is a condition in which a woman experiences
premature decline in ovarian function before the age of 40 years, manifested by menstrual …

Ovarian dysgenesis (OD), an XX disorder of sex development, presents with primary
amenorrhea, hypergonadotrophic hypogonadism, and infertility. In an Ashkenazi Jewish …

Meiosis in mammalian oocytes is interrupted by a prolonged arrest at the germinal vesicle
stage, during which oocytes have to repair DNA lesions to ensure genome integrity or …

Premature ovarian insufficiency (POI) is a common clinical disease of the reproductive
system in which patients lose normal gonadal function prior to the age of 40. Common …

The human female reproductive lifespan significantly diminishes with age, leading to
decreased fertility, reduced fertility quality and endocrine function disorders. While many …

Purpose To identify candidate variants in genes possibly associated with premature ovarian
insufficiency (POI). Methods Fourteen women, from 7 families, affected by idiopathic POI …

Research question Premature ovarian insufficiency (POI) is characterised by amenorrhea
associated with elevated follicle stimulating hormone (FSH) under the age of 40 years and …

Reproductive disorders are global health problems affecting millions of people worldwide. In
humans, infertility is indeed a very serious disease that disturbs also mental health. In …

Premature ovarian failure is a complex pathology with numerous etiologies and multiple
system sequelae resulting for early deprivation of ovarian sex hormones. In the studies to …