Interleukin-6 in biology and medicine

S Akira, T Taga, T Kishimoto - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on structure and expression of interleukin-6 (IL-6),
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …

Epstein-Barr virus infections: biology, pathogenesis, and management

SE Straus, JI Cohen, G Tosato… - Annals of internal medicine, 1993 - acpjournals.org
Epstein-Barr virus (EBV) encodes genes that ensure its persistence in human B
lymphocytes. Some of the genes encourage B-cell proliferation; others are poised to evade …

Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV

PS Moore, C Boshoff, RA Weiss, Y Chang - Science, 1996 - science.org
Four virus proteins similar to two human macrophage inflammatory protein (MIP)
chemokines, interleukin-6 (IL-6), and interferon regulatory factor (IRF) are encoded by the …

Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation

AL Taylor, R Marcus, JA Bradley - Critical reviews in oncology/hematology, 2005 - Elsevier
Post-transplant lymphoproliferative disorders (PTLD) are a well-recognised and potentially
fatal complication after solid organ transplantation. They include a spectrum of disorders …

Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice

E Tartour, F Fossiez, I Joyeux, A Galinha, A Gey… - Cancer research, 1999 - AACR
Interleukin (IL) 17 is a proinflammatory cytokine secreted mainly by activated human
memory CD4 T cells that induces IL-6, IL-8, and nitric oxide. Because IL-6 and IL-8 have …

Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome

L Fayad, MJ Keating, JM Reuben… - Blood, The Journal …, 2001 - ashpublications.org
The objective of this study was to examine the correlation between serum interleukin-6 (IL-6)
and IL-10 levels and outcome in chronic lymphocytic leukemia (CLL). Serum IL-6 and IL-10 …

Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease …

JWJ van Esser, B van der Holt, E Meijer… - Blood, The Journal …, 2001 - ashpublications.org
Reactivation of the Epstein-Barr virus (EBV) after allogeneic stem cell transplantation (allo-
SCT) may evoke a protective cellular immune response or may be complicated by the …

Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis

B Ebrahimi, SL Tucker, D Li… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Cytokines have been implicated in diverse processes that are relevant to
pancreatic carcinoma, including cachexia, asthenia, and tumor growth. The objective of this …

Epstein–Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-κB pathway

G Gatto, A Rossi, D Rossi, S Kroening… - Nucleic acids …, 2008 - academic.oup.com
Abstract The Epstein–Barr virus (EBV)-encoded latent membrane protein-1 (LMP1), a
functional homologue of the tumor necrosis factor receptor family, substantially contributes to …

Human B lymphocytes: phenotype, proliferation, and differentiation

J Banchereau, F Rousset - Advances in immunology, 1992 - Elsevier
Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …