Ketogenic diet does not promote triple-negative and luminal mammary tumor growth and metastasis in experimental mice

M Grube, A Dimmler, A Schmaus, R Saup… - Clinical & Experimental …, 2024 - Springer
Ketogenic diets (KDs) can improve the well-being and quality of life of breast cancer
patients. However, data on the effects of KDs on mammary tumors are inconclusive, and the …

[HTML][HTML] Anti-tumor effects of ketogenic diets and their synergism with other treatments in mice: Bayesian evidence synthesis of 1755 individual mouse survival data

RJ Klement - Biomedical Journal, 2024 - Elsevier
Abstract Background Ketogenic diets (KDs) are high-fat diets with putative anti-tumor effects.
The aim of this study was to synthesize the evidence for the anti-tumor effects of KDs in mice …

Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer

HT Langer, S Ramsamooj, E Dantas… - Acta …, 2024 - Wiley Online Library
Aim To investigate systemic regulators of the cancer‐associated cachexia syndrome (CACS)
in a pre‐clinical model for lung cancer with the goal to identify therapeutic targets for tissue …

Hepatic signal transducer and activator of transcription‐3 signalling drives early‐stage pancreatic cancer cachexia via suppressed ketogenesis

PC Arneson‐Wissink, H Mendez, K Pelz… - Journal of Cachexia …, 2024 - Wiley Online Library
Background Patients with pancreatic ductal adenocarcinoma (PDAC) often suffer from
cachexia, a wasting syndrome that significantly reduces both quality of life and survival …

IL-6/STAT3 signaling drives early-stage pancreatic cancer cachexia via suppressed ketogenesis

PC Arneson-Wissink, H Mendez, K Pelz, J Dickie… - bioRxiv, 2022 - biorxiv.org
Cancer cachexia is highly prevalent in patients with pancreatic ductal adenocarcinoma
(PDAC). Although advanced cachexia is associated with inflammatory signaling, the early …