To address the continued rise of multi-drug-resistant microorganisms, the development of
novel drugs with new modes of action is urgently required. While humans biosynthesize the …

deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) catalyzes the second step of the
non-mevalonate (or MEP) pathway that functions in several organisms and plants for the …

BACKGROUND The enzymes involved in the 2‐C‐methyl‐d‐erythritol 4‐phosphate (MEP)
pathway are attractive targets of a new mode of action for developing anti‐infective drugs …

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and its current
treatments have been complicated with the emergence of multi-drug resistant (MDR-TB) and …

Self-healing nanocomposites can be generated by organic functionalization of inorganic
nanoparticles and complementary functionalization of the polymer matrix, allowing …

A one‐pot Kabachnik‐Fields reaction is used in the presence of magnesium triflate [Mg (OTf)
2] as a catalyst between quinoline, diethyl phosphite (DEP), and substituted aldehydes to …

A rapid emergence in the incidences of Tuberculosis (TB) drug resistance undermines
efforts to eradicate the disease and strengthens calls for development of new drugs with …

With the emergence of antibiotic resistance, there is a growing concern that bacteria may
evolve resistance to all antimicrobials currently accessible, posing a severe health risk to all …

This chapter covers scientific contributions in quinquevalent organo-phosphorus chemistry
published in the literature in 2021. The review is not comprehensive but shows the most …

This chapter covers the literature published during 2019 relating to the synthesis and the
reactivity of tertiary phosphines, but excluding the chemistry of their metal complexes …