[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic

C Diener, A Keller, E Meese - Trends in Genetics, 2022 - cell.com
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

MicroRNA as an important target for anticancer drug development

Z Fu, L Wang, S Li, F Chen, KKW Au-Yeung… - Frontiers in …, 2021 - frontiersin.org
Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

Mitochondrial miRNAs (MitomiRs): their potential roles in breast and other cancers

E Erturk, OE Onur, O Akgun, G Tuna, Y Yildiz, F Ari - Mitochondrion, 2022 - Elsevier
Breast cancer is the most common cancer in women worldwide. MicroRNAs (miRNAs) are
non-coding RNAs that are involved in the post-transcriptional regulation of gene expression …

Bio-based nanomaterials for cancer therapy

Y Li, X Zheng, Q Chu - Nano Today, 2021 - Elsevier
Bio-based nanomaterials have received considerable attention in cancer therapies due to
their potent characteristics such as autologous pharmaceutical, synergetic effects …

Quantum dots: synthesis, antibody conjugation, and HER2-receptor targeting for breast cancer therapy

I Fatima, A Rahdar, S Sargazi, M Barani… - Journal of functional …, 2021 - mdpi.com
Breast cancer is becoming one of the main lethal carcinomas in the recent era, and its
occurrence rate is increasing day by day. There are different breast cancer biomarkers, and …

Trials and tribulations of MicroRNA therapeutics

AA Seyhan - International Journal of Molecular Sciences, 2024 - mdpi.com
The discovery of the link between microRNAs (miRNAs) and a myriad of human diseases,
particularly various cancer types, has generated significant interest in exploring their …

Surface engineered nanocarriers for the management of breast cancer

Y Nitheesh, R Pradhan, S Hejmady, R Taliyan… - Materials Science and …, 2021 - Elsevier
Breast cancer is commonly known life-threatening malignancy in women after lung cancer.
The standard of care (SOC) treatment for breast cancer primarily includes surgery …

Combinational application of metal–organic frameworks‐based nanozyme and nucleic acid delivery in cancer therapy

D Ni, J Lin, N Zhang, S Li, Y Xue… - Wiley …, 2022 - Wiley Online Library
The rapid development of nanotechnology has generated numerous ideas for cancer
treatment, and a wide variety of relevant nanoparticle platforms have been reported. Metal …

A comprehensive review of cancer therapies mediated by conjugated gold nanoparticles with nucleic acid

SA Hosseini, A Kardani, H Yaghoobi - International Journal of Biological …, 2023 - Elsevier
Nucleic acids provide a promising therapeutic platform by targeting various cell signaling
pathways involved in cancer and genetic disorders. However, maintaining optimal stability …