Abstract Band 3 protein (B3p), anion transporter, allows the HCO3−/Cl− exchange across
plasma membrane and plays an important role for erythrocytes homeostasis. In addition …

We review recent advances in multiscale modeling of the biomechanical characteristics of
red blood cells (RBCs) in hematological diseases, and their relevance to the structure and …

The spleen, the largest secondary lymphoid organ in humans, not only fulfils a broad range
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …

Super-resolution microscopy recently revealed that, unlike the soma and dendrites, the axon
membrane skeleton is structured as a series of actin rings connected by spectrin filaments …

Erythrocytes in patients with type-2 diabetes mellitus (T2DM) are associated with reduced
cell deformability and elevated blood viscosity, which contribute to impaired blood flow and …

We present OpenRBC, a coarse-grained molecular dynamics code, which is capable of
performing an unprecedented in silico experiment—simulating an entire mammal red blood …

Reticulocytes, the precursors of erythrocytes, undergo drastic alterations in cell size, shape,
and deformability during maturation. Experimental evidence suggests that young …

Healthy red blood cells (RBCs) have remarkable deformability, squeezing through narrow
capillaries as small as 3 microns in diameter without any damage. However, in many …

The spleen constantly clears altered red blood cells (RBCs) from the circulation, tuning the
balance between RBC formation (erythropoiesis) and removal. The retention and …

Differential counting of white blood cells (WBCs) in bone marrow using artificial intelligence
(AI)-based models, such as convolutional neural network (CNN) and its various variants, can …