Intervertebral disc degeneration: biomaterials and tissue engineering strategies toward precision medicine

IL Mohd Isa, SA Mokhtar, SA Abbah… - Advanced …, 2022 - Wiley Online Library
Intervertebral disc degeneration is a common cause of discogenic low back pain resulting in
significant disability. Current conservative or surgical intervention treatments do not reverse …

An overview of injectable polymeric hydrogels for tissue engineering

A Sivashanmugam, RA Kumar, MV Priya… - European Polymer …, 2015 - Elsevier
The desire and need to minimize traditional open surgeries is gearing up as it could reduce
the healthcare expenses and improve the recovery time for the patients. Minimal invasive …

[HTML][HTML] Construction of heparin-based hydrogel incorporated with Cu5. 4O ultrasmall nanozymes for wound healing and inflammation inhibition

Y Peng, D He, X Ge, Y Lu, Y Chai, Y Zhang, Z Mao… - Bioactive Materials, 2021 - Elsevier
Excessive production of inflammatory chemokines and reactive oxygen species (ROS) can
cause a feedback cycle of inflammation response that has a negative effect on cutaneous …

Recent progress in hyaluronic-acid-based hydrogels for bone tissue engineering

HS Hwang, CS Lee - Gels, 2023 - mdpi.com
Hydrogel-based bone tissue engineering is a potential strategy for treating bone
abnormalities and fractures. Hyaluronic acid (HA) is a natural polymer that is widely …

[PDF][PDF] Recent applications of polyethylene glycols (PEGs) and PEG derivatives

D Hutanu, MD Frishberg, L Guo, CC Darie - Mod. Chem. Appl, 2014 - jenkemusa.com
Numerous applications of polyethylene glycol derived polymers (PEGs) have been reported
in the scientific literature for many years. With increasing experience and comfort by …

The application of hyaluronic acid‐based hydrogels in bone and cartilage tissue engineering

H Li, Z Qi, S Zheng, Y Chang, W Kong… - … in Materials Science …, 2019 - Wiley Online Library
At present, the healing of osteopathy, especially the healing of cartilage, has been proven to
be difficult. Commonly used treatment methods are autogenous bone grafts and allogeneic …

Blends and composites of exopolysaccharides; properties and applications: A review

A Hussain, KM Zia, S Tabasum, A Noreen, M Ali… - International journal of …, 2017 - Elsevier
Exopolysaccharides are synthesized by bacteria and secreted into the external environment
and they may be homopolymeric or heteropolymeric in configuration. They are believed to …

Lessons learned from intervertebral disc pathophysiology to guide rational design of sequential delivery systems for therapeutic biological factors

L Frapin, J Clouet, V Delplace, M Fusellier… - Advanced Drug Delivery …, 2019 - Elsevier
Intervertebral disc (IVD) degeneration has been associated with low back pain, which is a
major musculoskeletal disorder and socio-economic problem that affects as many as 600 …

Gene therapy for regenerative medicine

H Hosseinkhani, AJ Domb, G Sharifzadeh, V Nahum - Pharmaceutics, 2023 - mdpi.com
The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

[HTML][HTML] Hyaluronic acid: a versatile biomaterial in tissue engineering

Z Zhu, YM Wang, J Yang, XS Luo - Plastic and Aesthetic Research, 2017 - oaepublish.com
The design and application of hyaluronic acid (HA)-based scaffolds to control cell response
and construct ideal tissue engineering products have been of great interest in the past few …