Urinary bladder cancer is a common malignancy, being characterized by substantial patient
mortality and management cost. Its high somatic-mutation frequency and molecular …

Histone deacetylases (HDACs) have long been implicated in tumorigenesis and tumor
progression demonstrating their important participation in neoplasia. Therefore, numerous …

Simple Summary Epigenetic changes occur in parts of the genome other than in
nucleotides. They are considered reversible and are therefore important targets for cancer …

Bladder cancer in the most advanced, muscle-invasive stage is lethal, and very limited
therapeutic advances have been reported for decades. To date, cisplatin-based …

Histone deacetylases (HDACs) have long been implicated in tumorigenesis and tumor
progression demonstrating their important participation in neoplasia. Therefore, numerous …

Epigenetics is a growing field and in bladder cancer, it is of particular interest in advanced or
metastatic disease. As opposed to genetic mutations in which the nucleotide sequence itself …

Epigenetics is a growing field and in bladder cancer, it is of particular interest in advanced or
metastatic disease. As opposed to genetic mutations in which the nucleotide sequence itself …

FGFR genomic alterations have been implicated in a number of cancers as oncogenesis
driver genes. However, despite the approval of several FGFR inhibitors as targeted …

Bladder cancer (BC) is one of the most prevalent malignancies worldwide and FGFR3
alterations are particularly common in BC. Despite approval of erdafitinib, durable …