Viruses infecting vertebrate hosts must overcome the interferon (IFN)-mediated antiviral
response to replicate and propagate to new hosts. The complex regulation of the IFN …

Double-stranded DNA (dsDNA) sensor cyclic-GMP-AMP synthase (cGAS) along with the
downstream stimulator of interferon genes (STING) acting as essential immune-surveillance …

A novel SARS-related coronavirus (SARS-CoV-2) has recently emerged as a serious
pathogen that causes high morbidity and substantial mortality. However, the mechanisms by …

African swine fever virus (ASFV) is a devastating infectious disease in pigs, severely
threatening the global pig industry. To efficiently infect animals, ASFV must evade or inhibit …

A characteristic feature of COVID‐19, the disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) infection, is the dysregulated immune response …

The emergence of SARS-CoV-2 has resulted in the COVID-19 pandemic, leading to millions
of infections and hundreds of thousands of human deaths. The efficient replication and …

Compared with terrestrial mammals, bats have a longer lifespan and greater capacity to co-
exist with a variety of viruses. In addition to cytosolic DNA generated by these viral …

Pseudorabies virus (PRV) has evolved various immune evasion mechanisms that target
host antiviral immune responses. However, it is unclear whether and how PRV encoded …

African swine fever is a severe animal infectious disease caused by African swine fever virus
(ASFV), and the morbidity and mortality associated with virulent ASFV isolates are as high …

Mitochondrial dysfunction and lysosomal dysfunction have been implicated in Parkinson's
disease (PD), but the links between these dysfunctions in PD pathogenesis are still largely …