The thyroid hormones play a pivotal role in various physiological processes, including
growth, metabolism regulation, and reproduction. While non-modifiable factors are known to …

Brain–heart interaction has raised up increasing attentions. Nuclear receptors (NRs) are
abundantly expressed in the brain, and emerging evidence indicates that a number of these …

The nutritional requirements of the developing embryo are complex. In the case of dietary
vitamin A (retinol, retinyl esters and provitamin A carotenoids), maternal derived nutrients …

The heart is the first organ to acquire its physiological function during development, enabling
it to supply the organism with oxygen and nutrients. Given this early commitment …

The retinol dehydrogenase Rdh10 catalyzes the rate-limiting reaction that converts retinol
into retinoic acid (RA), an autacoid that regulates energy balance and reduces adiposity …

High-dose radiation exposure results in hematopoietic (H) and gastrointestinal (GI) acute
radiation syndromes (ARS) followed by delayed effects of acute radiation exposure …

The incidence of cutaneous melanoma, a highly malignant skin cancer, is increasing yearly.
While surgical removal of the tumor is the mainstay of treatment for patients with locally …

Chronic inflammation is associated with lung tumorigenesis, in which NF-κB–mediated
epigenetic regulation plays a critical role. Lung tumor suppressor G protein–coupled …

During embryonic development, all blood progenitors are initially generated from
endothelial cells that acquire a hemogenic potential. Blood progenitors emerge through an …

Abstract Background Embryonic Sertoli cells (eSCs) have been known for playing important
roles in male reproductive development system. In current studies, eSCs were mainly …