Neuroprotective and Anti‐inflammatory Effects of Pioglitazone on Traumatic Brain Injury

MY Zamanian, N Taheri, MJC Opulencia… - Mediators of …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is still a major cause of concern for public health, and out of all
the trauma‐related injuries, it makes the highest contribution to death and disability …

Functional constituents of plant-based foods boost immunity against acute and chronic disorders

W Khalid, MS Arshad, MMAN Ranjha… - Open Life …, 2022 - degruyter.com
Plant-based foods are becoming an increasingly frequent topic of discussion, both scientific
and social, due to the dissemination of information and exchange of experiences in the …

Neuroprotective effects of gemfibrozil in neurological disorders: Focus on inflammation and molecular mechanisms

MS Ivraghi, MY Zamanian, R Gupta… - CNS Neuroscience …, 2024 - Wiley Online Library
Abstract Background Gemfibrozil (Gem) is a drug that has been shown to activate PPAR‐α,
a nuclear receptor that plays a key role in regulating lipid metabolism. Gem is used to lower …

Satureja khuzistanica Jamzad essential oil and pure carvacrol attenuate TBI-induced inflammation and apoptosis via NF-κB and caspase-3 regulation in the male rat …

E Abbasloo, S Amiresmaili, S Shirazpour… - Scientific Reports, 2023 - nature.com
Traumatic brain injury (TBI) causes progressive dysfunction that induces biochemical and
metabolic changes that lead to cell death. Nevertheless, there is no definitive FDA-approved …

Neuroprotective potential and underlying pharmacological mechanism of Carvacrol for Alzheimer's and Parkinson's Diseases

H Javed, NM Mohamed Fizur… - Current …, 2023 - benthamdirect.com
The phytochemicals have antioxidant properties to counter the deleterious effects of
oxidative stress in the central nervous system and can be a promising drug candidate for …

Targeting Nrf2 signaling pathway by quercetin in the prevention and treatment of neurological disorders: An overview and update on new developments

MY Zamanian, A Soltani, Z Khodarahmi… - Fundamental & …, 2023 - Wiley Online Library
Abstract Background: Neurological disorders (NLDs) are widely acknowledged as a
significant public health concern worldwide. Stroke, Alzheimer's disease (AD), and traumatic …

Recent advances in the pharmacological properties and molecular mechanisms of carvacrol

T Ali, ST Majeed, R Majeed, R Bashir, SA Mir… - Revista Brasileira de …, 2024 - Springer
Plant secondary metabolites have received a lot of attention for their immense
pharmacological activities and low side effects. Monoterpenes, belonging to the terpene …

Dietary monoterpenoids and human health: Unlocking the potential for therapeutic use

B Vyhlídalová, K Ondrová, I Zůvalová - Biochimie, 2024 - Elsevier
Natural products are widely used in different aspects of our lives–from household cleaners
and food production, via cosmetics and aromatherapy, to both alternative and traditional …

Therapeutic effects of carvacrol on beta‐amyloid‐induced impairments in in vitro and in vivo models of Alzheimer's disease

K Celik Topkara, E Kilinc, A Cetinkaya… - European Journal of …, 2022 - Wiley Online Library
Due to the complex nature of Alzheimer's disease (AD), it is important to investigate agents
with multiple effects in the treatment of AD. Carvacrol possesses anti‐acetylcholinesterase …

Mapping new pharmacological interventions for cognitive function in Alzheimer's disease: a systematic review of randomized clinical trials

I Xu Lou, J Chen, K Ali, AL Shaikh… - Frontiers in Pharmacology, 2023 - frontiersin.org
Background and Objective: Alzheimer's disease (AD) is a progressive neurodegenerative
disorder, that is, characterized by cognitive decline. To date, there are no effective …