The Landscape of long noncoding RNA classification

GS Laurent, C Wahlestedt, P Kapranov - Trends in genetics, 2015 - cell.com
Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …

Intron retention in mRNA: No longer nonsense: Known and putative roles of intron retention in normal and disease biology

JJL Wong, AYM Au, W Ritchie, JEJ Rasko - Bioessays, 2016 - Wiley Online Library
Until recently, retention of introns in mature mRNAs has been regarded as a consequence of
mis‐splicing. Intron‐retaining transcripts are thought to be non‐functional because they are …

Long noncoding RNA EGFR-AS1 promotes cell growth and metastasis via affecting HuR mediated mRNA stability of EGFR in renal cancer

A Wang, Y Bao, Z Wu, T Zhao, D Wang, J Shi… - Cell death & …, 2019 - nature.com
Long noncoding RNAs (lncRNAs) are implicated in renal cell carcinoma (RCC), but remain
largely unclear. Using publicly available transcriptome sequencing data from renal cancer …

Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer

M Ma, C Li, Y Zhang, M Weng, M Zhang, Y Qin… - Molecular cancer, 2014 - Springer
Background Protein coding genes account for only about 2% of the human genome,
whereas the vast majority of transcripts are non-coding RNAs including long non-coding …

Cancer specific long noncoding RNAs show differential expression patterns and competing endogenous RNA potential in hepatocellular carcinoma

J Zhang, D Fan, Z Jian, GG Chen, PBS Lai - PloS one, 2015 - journals.plos.org
Long noncoding RNAs (lncRNAs) regulate gene expression by acting with microRNAs
(miRNAs). However, the roles of cancer specific lncRNA and its related competitive …

A four-long non-coding RNA signature in predicting breast cancer survival

J Meng, P Li, Q Zhang, Z Yang, S Fu - Journal of experimental & clinical …, 2014 - Springer
Background Many long non-coding RNAs (lncRNAs) have been found to be a good marker
for several tumors. Using lncRNA-mining approach, we aimed to identify lncRNA expression …

A serum-circulating long noncoding RNA signature can discriminate between patients with clear cell renal cell carcinoma and healthy controls

Y Wu, YQ Wang, WW Weng, QY Zhang, XQ Yang… - Oncogenesis, 2016 - nature.com
Serum biomarkers have not been fully incorporated into clinical use for the diagnosis of
renal cell carcinoma (RCC). The recent discovery of long noncoding RNAs (lncRNAs), which …

Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-κB …

J Ji, R Xu, K Ding, G Bao, X Zhang, B Huang… - Clinical Cancer …, 2019 - AACR
Abstract Purpose: Long noncoding RNAs (lncRNA) have essential roles in diverse cellular
processes, both in normal and diseased cell types, and thus have emerged as potential …

An emerging understanding of long noncoding RNAs in kidney cancer

S Zhou, J Wang, Z Zhang - Journal of cancer research and clinical …, 2014 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) are pervasively transcribed in the
genome and are emerging as new players in tumorigenesis. Methods An electronic search …

Integrated analysis of co‐expression and ceRNA network identifies five lncRNAs as prognostic markers for breast cancer

Y Yao, T Zhang, L Qi, C Zhou, J Wei… - Journal of Cellular …, 2019 - Wiley Online Library
Long non‐coding RNAs (lncRNAs), which competitively bind miRNAs to regulate target
mRNA expression in the competing endogenous RNAs (ceRNAs) network, have attracted …