Significance: Oxidative stress represents the common hallmark of pathological conditions
associated with cardiovascular disease (CVD), including atherosclerosis, heart failure …

Abstract Silent information regulator-2 (Sir-2) proteins, or sirtuins, are a highly conserved
protein family of histone deacetylases that promote longevity by mediating many of the …

Background Few studies explored the effect of the combination of glucose sodium-
cotransporter-2 inhibitors (SGLT-2i) and glucagon-like peptide-1 receptor agonists (GLP …

Primary percutaneous coronary intervention (PPCI) is a pivotal treatment in ST‐segment
elevation myocardial infarction (STEMI) patients. However, in hyperglycemic‐STEMI …

Background: Sirtuin1 is an epigenetic enzyme involved in histone and nonhistone protein
deacetylation. It acts primarily as a metabolic sensor, which responses to changing energy …

Diabetes is a highly prevalent disease associated with considerable cardiovascular end
organ damage and mortality. Despite significant changes to the management of acute …

Aims To evaluate the predictive value of fasting stress hyperglycemia ratio (SHR) for in-
hospital mortality in patients with acute myocardial infarction (AMI) under different glucose …

Elevation of glucose level in response to acute coronary syndrome (ACS) has been
recognized as stress induced hyperglycemia (SIH). Plenty of clinical studies have …

Acute ST-segment elevation myocardial infarction (STEMI) activates inflammation that can
contribute to left ventricular systolic dysfunction (LVSD) and heart failure (HF). The objective …

Objective: Ventricular remodeling is considered the basis of heart failure and is involved in
myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor …