[HTML][HTML] Polyoxidovanadates' interactions with proteins: An overview

M Aureliano, NI Gumerova, G Sciortino… - Coordination Chemistry …, 2022 - Elsevier
Polyoxidovanadates (POVs, previously named polyoxovanadates) are a subgroup of
polyoxidometalates (POMs, previously named polyoxometalates) with interesting …

Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetes mellitus

S Treviño, A Díaz, E Sánchez-Lara… - Biological trace element …, 2019 - Springer
Vanadium compounds have been primarily investigated as potential therapeutic agents for
the treatment of various major health issues, including cancer, atherosclerosis, and …

Developing vanadium as an antidiabetic or anticancer drug: A clinical and historical perspective

DC Crans, L Henry, G Cardiff, BI Posner - Met. Ions Life Sci, 2019 - degruyter.com
Vanadium has been known for centuries to have beneficial effects on health and has the
potential to be used as an alternative to other diabetic and anticancer medicines. The …

Vanadium, ruthenium and copper compounds: a new class of nonplatinum metallodrugs with anticancer activity

I Esteban Leon… - Current medicinal …, 2017 - ingentaconnect.com
Cancer is a group of diseases involving abnormal cell growth. The cells grow uncontrollably
with the potential to invade and spread to other parts of the body. This disease is one of the …

Vanadium and insulin: Partners in metabolic regulation

S Treviño, A Diaz - Journal of Inorganic Biochemistry, 2020 - Elsevier
Since the 1970s, the biological role of vanadium compounds has been discussed as insulin-
mimetic or insulin-enhancer agents. The action of vanadium compounds has been …

Health benefits of vanadium and its potential as an anticancer agent

DC Crans, L Yang, A Haase, X Yang - Met. Ions Life Sci, 2018 - degruyter.com
Vanadium compounds have been known to have beneficial therapeutic properties since the
turn of the century, but it was not until 1965 when it was discovered that those effects could …

[HTML][HTML] Decavanadate and metformin-decavanadate effects in human melanoma cells

AL De Sousa-Coelho, M Aureliano, G Fraqueza… - Journal of Inorganic …, 2022 - Elsevier
Decavanadate is a polyoxometalate (POMs) that has shown extensive biological activities,
including antidiabetic and anticancer activity. Importantly, vanadium-based compounds as …

Why antidiabetic vanadium complexes are not in the pipeline of “big pharma” drug research? A critical review

T Scior, J Antonio Guevara-Garcia… - Current medicinal …, 2016 - ingentaconnect.com
Public academic research sites, private institutions as well as small companies have made
substantial contributions to the ongoing development of antidiabetic vanadium compounds …

Biological properties of transition metal complexes with metformin and its analogues

DA Rusanov, J Zou, MV Babak - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely prescribed medication for the treatment and management of type 2
diabetes. It belongs to a class of biguanides, which are characterized by a wide range of …

Repurposing therapeutic drugs complexed to vanadium in cancer

AL De Sousa-Coelho, G Fraqueza, M Aureliano - Pharmaceuticals, 2023 - mdpi.com
Repurposing drugs by uncovering new indications for approved drugs accelerates the
process of establishing new treatments and reduces the high costs of drug discovery and …