ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

CAR T cells for brain tumors: Lessons learned and road ahead

D Akhavan, D Alizadeh, D Wang, MR Weist… - Immunological …, 2019 - Wiley Online Library
Malignant brain tumors, including glioblastoma, represent some of the most difficult to treat
of solid tumors. Nevertheless, recent progress in immunotherapy, across a broad range of …

In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift

A Kheirolomoom, AJ Kare, ES Ingham, R Paulmurugan… - Biomaterials, 2022 - Elsevier
Ex vivo programming of T cells can be efficacious but is complex and expensive; therefore,
the development of methods to transfect T cells in situ is important. We developed and …

Molecular imaging of chimeric antigen receptor T cells by ICOS-ImmunoPET

F Simonetta, IS Alam, JK Lohmeyer, B Sahaf… - Clinical Cancer …, 2021 - AACR
Purpose: Immunomonitoring of chimeric antigen receptor (CAR) T cells relies primarily on
their quantification in the peripheral blood, which inadequately quantifies their …

ICOS is an indicator of T-cell–mediated response to cancer immunotherapy

Z Xiao, AT Mayer, TW Nobashi, SS Gambhir - Cancer research, 2020 - AACR
Immunotherapy is innovating clinical cancer management. Nevertheless, only a small
fraction of patient's benefit from current immunotherapies. To improve clinical management …

Theranostic chimeric antigen receptor (CAR)-T cells: Insight into recent trends and challenges in solid tumors

K Kheyrolahzadeh, MR Tohidkia, A Tarighatnia… - Life Sciences, 2023 - Elsevier
Cell therapy has reached significant milestones in various life-threatening diseases,
including cancer. Cell therapy using fluorescent and radiolabeled chimeric antigen receptor …

Emerging biomaterials imaging antitumor immune response

X Ma, MJ Zhang, J Wang, T Zhang, P Xue… - Advanced …, 2022 - Wiley Online Library
Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …

[HTML][HTML] Imaging of T-cells and their responses during anti-cancer immunotherapy

M Krekorian, GO Fruhwirth, M Srinivas, CG Figdor… - Theranostics, 2019 - ncbi.nlm.nih.gov
Imaging of T-cells and their responses during anti-cancer immunotherapy - PMC Back to Top
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ImmunoPET: antibody-based PET imaging in solid tumors

R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …