Cutaneous T-cell lymphoma (CTCL) poses unique treatment challenges, given its range of
presentations and numerous systemic therapy options. These options often lack …

New treatments are needed for patients with cutaneous T‐cell lymphoma (CTCL),
particularly for advanced mycosis fungoides (MF) and Sezary syndrome (SS). The …

Cancer metastasis is a leading cause of cancer morbidity and mortality. More needs to be
learned about mechanisms that control this process. In particular, the role of chemokine …

Altering the immunosuppressive microenvironment that exists within a tumor will likely be
necessary for cancer vaccines to trigger an effective antitumor response. Monocyte …

The possible therapeutic benefits of B-cell depletion in combating tumoral immune escape
have been debated. In support of this concept, metastasis of highly aggressive 4T1 breast …

Targeted therapy has replaced the conventional methods of disease management with the
advances in recombinant technology and increased understanding of molecular …

Pulmonary fibrosis (PF) is a type of fatal respiratory diseases with limited therapeutic options
and poor prognosis. The chemokine CCL17 plays crucial roles in the pathogenesis of …

Importance of the field: Psoriasis is a common, chronic autoimmune disease of the skin.
Despite a number of effective treatments, new therapies are needed with enhanced efficacy …

Chemokine receptors are G-protein-coupled, seven-transmembrane-spanning surface
receptors that play key roles in cell trafficking, cell motility, and survival. These receptors are …

Breast cancer (BC) is the most common cancer among women between the ages of 20 and
50, affecting more than 2.1 million people and causing the annual death of more than …