[HTML][HTML] Transfer RNA modification and infection–implications for pathogenicity and host responses

C San Koh, LP Sarin - Biochimica et Biophysica Acta (BBA)-Gene …, 2018 - Elsevier
Transfer RNA (tRNA) molecules are sumptuously decorated with evolutionary conserved
post-transcriptional nucleoside modifications that are essential for structural stability and …

LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella

W Elhenawy, M Bording-Jorgensen, E Valguarnera… - MBio, 2016 - Am Soc Microbiol
Outer membrane vesicles (OMV) are proposed to mediate multiple functions during
pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation …

[HTML][HTML] tRNA modification enzymes GidA and MnmE: potential role in virulence of bacterial pathogens

DC Shippy, AA Fadl - International journal of molecular sciences, 2014 - mdpi.com
Transfer RNA (tRNA) is an RNA molecule that carries amino acids to the ribosomes for
protein synthesis. These tRNAs function at the peptidyl (P) and aminoacyl (A) binding sites …

A tRNA modifying enzyme as a tunable regulatory nexus for bacterial stress responses and virulence

BA Fleming, MG Blango, AA Rousek… - Nucleic acids …, 2022 - academic.oup.com
Post-transcriptional modifications can impact the stability and functionality of many different
classes of RNA molecules and are an especially important aspect of tRNA regulation. It is …

tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa

J Krueger, M Preusse… - Proceedings of the …, 2024 - National Acad Sciences
The success of bacterial pathogens depends on the coordinated expression of virulence
determinants. Regulatory circuits that drive pathogenesis are complex, multilayered, and …

GidA, a tRNA Modification Enzyme, Contributes to the Growth, and Virulence of Streptococcus suis Serotype 2

T Gao, M Tan, W Liu, C Zhang, T Zhang… - Frontiers in cellular …, 2016 - frontiersin.org
Glucose-inhibited division protein (GidA), is a tRNA modification enzyme functioning
together with MnmE in the addition of a carboxymethylaminomethyl group to position 5 of the …

Pseudomonas aeruginosa GidA modulates the expression of catalases at the posttranscriptional level and plays a role in virulence

T Srimahaeak, N Thongdee, J Chittrakanwong… - Frontiers in …, 2023 - frontiersin.org
Pseudomonas aeruginosa gidA, which encodes a putative tRNA-modifying enzyme, is
associated with a variety of virulence phenotypes. Here, we demonstrated that P …

LC_Glucose-Inhibited Division Protein Is Required for Motility, Biofilm Formation, and Stress Response in Lysobacter capsici X2-3

D Zhao, H Wang, Z Li, S Han, C Han, A Liu - Frontiers in Microbiology, 2022 - frontiersin.org
Glucose-inhibited division protein (GidA) plays a critical role in the growth, stress response,
and virulence of bacteria. However, how gidA may affect plant growth-promoting bacteria …

RNA modification enzymes encoded by the gid operon: Implications in biology and virulence of bacteria

DC Shippy, AA Fadl - Microbial pathogenesis, 2015 - Elsevier
Ribonucleic acid (RNA) molecules consist of numerous chemically modified nucleosides
that are highly conserved in eukarya, archeae, and bacteria, while others are unique to each …

The Transcription Regulator GntR/HutC Regulates Biofilm Formation, Motility and Stress Tolerance in Lysobacter capsici X2-3

D Zhao, J Wang, H Wang, X Zhu, C Han, A Liu - Current Microbiology, 2023 - Springer
Abstract Lysobacter capsici X2-3, a plant growth-promoting rhizobacteria (PGPR), was
isolated from wheat rhizosphere and has inhibitory effects against a wide range of …