Control of metalloenzyme activity using photopharmacophores

NN Mafy, DB Hudson, EL Que - Coordination Chemistry Reviews, 2024 - Elsevier
Metalloenzymes are responsible for numerous physiological and pathological processes in
living organisms; however, there are very few FDA-approved metalloenzyme-targeting …

Fragment-to-Lead Medicinal Chemistry Publications in 2023

RS Holvey, DA Erlanson, IJP de Esch… - Journal of medicinal …, 2025 - ACS Publications
This Perspective summarizes successful fragment-to-lead (F2L) studies that were published
in 2023 and is the ninth installment in an annual series. A tabulated summary of the relevant …

[HTML][HTML] Geometry optimization, impact of solvation on the spectral (FT-IR, UV, NMR) analysis, Quantum chemical parameters, and the bioactivity of feruloyltyramine as …

AE Eyo, GA Obadiah, I Benjamin, UO Edet… - Chemical Physics …, 2023 - Elsevier
The unrelenting menace of the Lassa virus, characterized by its high mortality rate and the
potential for global dissemination, underscores an urgent call for its comprehensive …

Inhibition of human epidermal growth factor receptor-2 protein by some alkaloid inhibitors

L Razavi, H Raissi - Journal of Molecular Liquids, 2024 - Elsevier
Abstract Background Human Epidermal Growth Factor Receptor-2 (HER2), a
transmembrane tyrosine kinase receptor, has been associated with several types of cancer …

[PDF][PDF] Chemical Physics Impact

AE Eyo, GA Obadiah, I Benjamin, UO Edet, FO Akor… - researchgate.net
The unrelenting menace of the Lassa virus, characterized by its high mortality rate and the
potential for global dissemination, underscores an urgent call for its comprehensive …