Adenosine triphosphate (ATP) is one of the main biochemical components of the tumor
microenvironment (TME), where it can promote tumor progression or tumor suppression …

Adenosine triphosphate (ATP) has been well established as an important extracellular
ligand of autocrine signaling, intercellular communication, and neurotransmission with …

Sheppard, David N., and Michael J. Welsh. Structure and Function of the CFTR Chloride
Channel. Physiol. Rev. 79, Suppl.: S23–S45, 1999.—The cystic fibrosis transmembrane …

Extracellular adenosine triphosphate (ATP) serves as a signal for diverse physiological
functions, including spread of calcium waves between astrocytes, control of vascular oxygen …

Abstract The nucleotide adenosine 5′-triphosphate (ATP) has classically been considered
the cell's primary energy currency. Importantly, a novel role for ATP as an extracellular …

Extracellular nucleotides and nucleosides promote a vast range of physiological responses,
via activation of cell surface purinergic receptors. Virtually all tissues and cell types exhibit …

The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

The ability for long-range communication through intercellular calcium waves is inherent to
cells of many tissues. A dual propagation mode for these waves includes passage of IP3 …

The concept that adenine and uridine nucleotides function as extracellular signaling
molecules has been markedly expanded in the last decade. At least 15 nucleotide-activated …

The maintenance of a constant volume in the face of extracellular and intracellular osmotic
perturbation is essential for the normal function and survival of animal cells. Osmotically …