A comprehensive review of beetroot (Beta vulgaris L.) bioactive components in the food and pharmaceutical industries

M Thiruvengadam, IM Chung… - Critical Reviews in …, 2024 - Taylor & Francis
Beetroot is rich in various bioactive phytochemicals, which are beneficial for human health
and exert protective effects against several disease conditions like cancer, atherosclerosis …

Will the interactions of some platinum (II)-Based drugs with B-vitamins reduce their therapeutic effect in cancer patients? Comparison of chemotherapeutic agents such …

B Szefler, P Czeleń - International Journal of Molecular Sciences, 2023 - mdpi.com
Pt (II) derivatives show anti-cancer activity by interacting with nucleobases of DNA, thus
causing some spontaneous and non-spontaneous reactions. As a result, mono-and diaqua …

Complementary and alternative therapies in oncology

A Dawczak-Dębicka, J Kufel-Grabowska… - International Journal of …, 2022 - mdpi.com
Cancer is the second leading cause of death worldwide, after cardiovascular diseases.
Increasing patients' awareness and providing easier access to public information result in …

Interplay between thiamine and p53/p21 axes affects antiproliferative action of cisplatin in lung adenocarcinoma cells by changing metabolism of 2-oxoglutarate …

VA Aleshin, X Zhou, S Krishnan, A Karlsson… - Frontiers in …, 2021 - frontiersin.org
Thiamine (vitamin B1) is often deficient in oncopatients, particularly those undergoing
chemotherapy. However, interaction between the thiamine deficiency and anticancer action …

The affinity of carboplatin to B-vitamins and nucleobases

B Szefler, P Czeleń, P Krawczyk - International Journal of Molecular …, 2021 - mdpi.com
Platinum compounds have found wide application in the treatment of various types of cancer
and carboplatin is one of the main platinum-based drugs used as antitumor agents. The …

What is the Reason That the Pharmacological Future of Chemotherapeutics in the Treatment of Lung Cancer Could Be Most Closely Related to Nanostructures …

K Szupryczyński, P Czeleń, T Jeliński… - International Journal of …, 2024 - Taylor & Francis
Over the course of several decades, anticancer treatment with chemotherapy drugs for lung
cancer has not changed significantly. Unfortunately, this treatment prolongs the patient's life …

Affinities to Oxaliplatin: Vitamins from B Group vs. Nucleobases

B Szefler, P Czeleń, K Wojtkowiak… - International Journal of …, 2022 - mdpi.com
Oxaliplatin, similar to Cisplatin, exhibits anticancer activity by interacting with DNA and
inducing programmed cell death. It is biotransformed through a number of spontaneous and …

DFT Calculations of the structural, mechanical, and electronic properties of TiV alloy under high pressure

F Yu, Y Liu - Symmetry, 2019 - mdpi.com
A calculation program based on the density functional theory (DFT) is applied to study the
structural, mechanical, and electronic properties of TiV alloys with symmetric structure under …

The assessment of physicochemical properties of Cisplatin complexes with purines and vitamins B group

B Szefler, P Czeleń, S Kruszewski… - Journal of Molecular …, 2022 - Elsevier
The positively charged products of Cisplatin hydrolysis can form bonds with Guanine and
Adenine, showing the ability to crosslink with nucleobases within the double helical DNA …

Docking of cisplatin on fullerene derivatives and some cube rhombellane functionalized homeomorphs

B Szefler, P Czeleń - Symmetry, 2019 - mdpi.com
Cisplatin (cisPt) is one of the strongest anticancer agents with proven clinical activity against
a wide range of solid tumors. Its mode of action has been linked to its ability to crosslink with …