Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

Endometrial stem/progenitor cells: the first 10 years

CE Gargett, KE Schwab… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND The existence of stem/progenitor cells in the endometrium was postulated
many years ago, but the first functional evidence was only published in 2004. The …

Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts

A Muraoka, M Suzuki, T Hamaguchi… - Science translational …, 2023 - science.org
Retrograde menstruation is a widely accepted cause of endometriosis. However, not all
women who experience retrograde menstruation develop endometriosis, and the …

Endometriosis-associated macrophages: origin, phenotype, and function

C Hogg, AW Horne, E Greaves - Frontiers in endocrinology, 2020 - frontiersin.org
Endometriosis is a complex, heterogeneous, chronic inflammatory condition impacting~ 176
million women worldwide. It is associated with chronic pelvic pain, infertility, and fatigue, and …

[HTML][HTML] Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

[HTML][HTML] Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis

R Forster, A Sarginson, A Velichkova, C Hogg… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Endometriosis is a common incurable inflammatory disorder that is associated with
debilitating pelvic pain in women. Macrophages are central to the pathophysiology of …

Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche

Y Henlon, K Panir, I McIntyre, C Hogg, P Dhami… - Proceedings of the …, 2024 - pnas.org
Endometriosis negatively impacts the health-related quality of life of 190 million women
worldwide. Novel advances in nonhormonal treatments for this debilitating condition are …

Research priorities for endometriosis: recommendations from a global consortium of investigators in endometriosis

PAW Rogers, GD Adamson, M Al-Jefout… - Reproductive …, 2017 - journals.sagepub.com
The 3rd International Consensus Workshop on Research Priorities in Endometriosis was
held in São Paulo on May 4, 2014, following the 12th World Congress on Endometriosis …

Endometriosis: current challenges in modeling a multifactorial disease of unknown etiology

H Malvezzi, EB Marengo, S Podgaec… - Journal of Translational …, 2020 - Springer
Endometriosis is a chronic inflammatory hormone-dependent condition associated with
pelvic pain and infertility, characterized by the growth of ectopic endometrium outside the …

Autonomic nervous system and inflammation interaction in endometriosis-associated pain

Y Wei, Y Liang, H Lin, Y Dai, S Yao - Journal of neuroinflammation, 2020 - Springer
Endometriosis is a chronic inflammatory disease. Pain is the most common symptom in
endometriosis. Endometriosis-associated pain is caused by inflammation, and is related to …