Alzheimer's disease (AD) is a major subtype of neurodegenerative dementia caused by long-
term interactions and accumulation of multiple adverse factors, accompanied by …

Alzheimer's disease (AD) is the main type of dementia and is a disease with a profound
socioeconomic burden due to the lack of effective treatment. In addition to genetics and …

The loss of cognitive function in Alzheimer's disease is pathologically linked with
neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral …

Alzheimer's disease (AD) is the most prevalent form of dementia in the elderly population
and has worldwide impact. The etiology of the disease is complex and results from the …

Down syndrome (DS) is the most frequent genetic cause of intellectual disability and is
strongly associated with Alzheimer's disease (AD). Brain insulin resistance greatly …

Fructose consumption has drastically increased during the last decades due to the extensive
commercial use of high-fructose corn syrup as a sweetener for beverages, snacks and …

Alzheimer's Disease (AD) is a global chronic disease in adults with beta-amyloid (Aβ)
deposits and hyperphosphorylated tau protein as the pathologic characteristics. Although …

Alzheimer's disease (AD) represents a progressive amyloidogenic disorder whose
advancement is widely recognized to be connected to amyloid-β peptides and Tau …

Alzheimer's disease (AD) is a multifactorial disease, and it has become a serious health
problem in the world. Senile plaques (SPs) and neurofibrillary tangles (NFTs) are two main …

Dysregulation of brain insulin signaling with reduced downstream neuronal survival and
plasticity mechanisms are fundamental abnormalities observed in Alzheimer disease (AD) …