Gulf War illness: mechanisms underlying brain dysfunction and promising therapeutic strategies

B Dickey, LN Madhu, AK Shetty - Pharmacology & therapeutics, 2021 - Elsevier
Abstract Gulf War Illness (GWI), a chronic multisymptom health problem, afflicts~ 30% of
veterans served in the first GW. Impaired brain function is among the most significant …

Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans

LT Michalovicz, KA Kelly, K Sullivan, JP O'Callaghan - Neuropharmacology, 2020 - Elsevier
Abstract Gulf War Illness (GWI) is a chronic multi-symptom disorder, characterized by
symptoms such as fatigue, pain, cognitive and memory impairment, respiratory, skin and …

Mitochondrial impairment but not peripheral inflammation predicts greater Gulf War illness severity

BA Golomb, R Sanchez Baez, JM Schilling… - Scientific reports, 2023 - nature.com
Gulf War illness (GWI) is an important exemplar of environmentally-triggered chronic
multisymptom illness, and a potential model for accelerated aging. Inflammation is the main …

Examining the current health of Gulf War veterans with the veterans affairs frailty index

LL Chao - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Gulf War Illness (GWI) is a chronic, multisymptom (eg, fatigue, muscle/joint pain,
memory and concentration difficulties) condition estimated to affect 25–32% of Gulf War …

Paraoxonase role in human neurodegenerative diseases

CO Reichert, D Levy, SP Bydlowski - Antioxidants, 2020 - mdpi.com
The human body has biological redox systems capable of preventing or mitigating the
damage caused by increased oxidative stress throughout life. One of them are the …

Neuropsychological findings in Gulf War illness: a review

MG Jeffrey, M Krengel, JL Kibler, C Zundel… - Frontiers in …, 2019 - frontiersin.org
This review paper summarizes the accumulation of research investigating
neuropsychological outcomes in veterans with Gulf War illness (GWI). Earlier research …

Experiential avoidance is associated with medical and mental health diagnoses in a national sample of deployed Gulf War veterans

SM Blakey, TF Halverson, MK Evans, TA Patel… - Journal of Psychiatric …, 2021 - Elsevier
A substantial minority of deployed Gulf War veterans developed posttraumatic stress
disorder (PTSD), depression, and several chronic illnesses. Although military combat and …

The gut-microbiome in Gulf War veterans: a preliminary report

PA Janulewicz, RK Seth, JM Carlson, J Ajama… - International journal of …, 2019 - mdpi.com
Gulf War Illness (GWI) is a chronic multi-symptom disorder affecting the central nervous
system (CNS), immune and gastrointestinal (GI) systems of Gulf War veterans (GWV). We …

Chemical exposures and suspected impact on Gulf War Veterans

R Elhaj, JM Reynolds - Military Medical Research, 2023 - Springer
Abstract Gulf War Illness (GWI) encompass a spectrum of maladies specific to troops
deployed during the Persian Gulf War (1990–1991). There are several hypothesized factors …

Depleted uranium and Gulf War Illness: Updates and comments on possible mechanisms behind the syndrome

G Bjørklund, L Pivina, M Dadar, Y Semenova… - Environmental …, 2020 - Elsevier
Indications of proximal tubule effects have been observed in recent surveillance study of
Gulf War veterans exposed to depleted uranium (DU). This gives some support for the …