Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

The global spread of antibiotic resistance genes (ARGs) has wreaked havoc with the
treatment efficiency of antibiotics and, ultimately, anti-microbial chemotherapy, and has been …

P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …

The antimicrobial resistance crisis is a global health issue requiring discovery and
development of novel therapeutics. However, conventional screening of natural products or …

Drug resistance represents a great concern among people with cystic fibrosis (CF), due to
the recurrent and prolonged antibiotic therapy they should often undergo. Among Multi Drug …

Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …

Highlights•RND pumps of P. aeruginosa and A. baumannii, fall into three different
categories.•The three categories of efflux pumps participate in different physiological …

Over the past few decades, antimicrobial resistance (AMR) has emerged as an important
threat to public health, resulting from the global propagation of multidrug-resistant strains of …

The emergence and spread of bacteria resistant to commonly used antibiotics poses a
critical threat to modern medical practice. Multiple classes of bacterial efflux pump systems …

Textbook procedures require the use of individual aptamers enriched in SELEX libraries
which are subsequently chemically synthesized after their biochemical characterization …