Inherited and acquired immunodeficiencies underlying tuberculosis in childhood
S Boisson‐Dupuis, J Bustamante… - Immunological …, 2015 - Wiley Online Library
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb) and a few related
mycobacteria, is a devastating disease, killing more than a million individuals per year …
mycobacteria, is a devastating disease, killing more than a million individuals per year …
The hyper IgM syndromes: Epidemiology, pathogenesis, clinical manifestations, diagnosis and management
Abstract Hyper Immunoglobulin M syndrome (HIGM) is a rare primary immunodeficiency
disorder characterized by low or absent levels of serum IgG, IgA, IgE and normal or …
disorder characterized by low or absent levels of serum IgG, IgA, IgE and normal or …
A B1a–natural IgG–neutrophil axis is impaired in viral-and steroid-associated aspergillosis
The lung naturally resists Aspergillus fumigatus (Af) in healthy individuals, but multiple
conditions can disrupt this resistance, leading to lethal invasive infections. Core processes …
conditions can disrupt this resistance, leading to lethal invasive infections. Core processes …
Long-term outcomes of 176 patients with X-linked hyper-IgM syndrome treated with or without hematopoietic cell transplantation
MT de la Morena, D Leonard, TR Torgerson… - Journal of Allergy and …, 2017 - Elsevier
Background X-linked hyper-IgM syndrome (XHIGM) is a primary immunodeficiency with high
morbidity and mortality compared with those seen in healthy subjects. Hematopoietic cell …
morbidity and mortality compared with those seen in healthy subjects. Hematopoietic cell …
[HTML][HTML] ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious …
Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …
Clinical phenotypes of hyper-IgM syndromes
MT de la Morena - The Journal of Allergy and Clinical Immunology: In …, 2016 - Elsevier
The primary immunodeficiency (PID) diseases comprise a heterogeneous group of inherited
disorders of immune function. Technical advancements in whole-genome, whole-exome …
disorders of immune function. Technical advancements in whole-genome, whole-exome …
Cystoisospora belli infections in humans: the past 100 years
Cystoisospora belli is a coccidian parasite of humans, with a direct fecal–oral transmission
cycle. It is globally distributed, but mainly found in tropical and subtropical areas. Many …
cycle. It is globally distributed, but mainly found in tropical and subtropical areas. Many …
Hyper IgM syndrome: a report from the USIDNET registry
EA Leven, P Maffucci, HD Ochs, PR Scholl… - Journal of clinical …, 2016 - Springer
Abstract Purpose The United States Immunodeficiency Network (USIDNET) patient registry
was used to characterize the presentation, genetics, phenotypes, and treatment of patients …
was used to characterize the presentation, genetics, phenotypes, and treatment of patients …
Lung disease in primary antibody deficiencies
E Schussler, MB Beasley, PJ Maglione - The Journal of Allergy and Clinical …, 2016 - Elsevier
Primary antibody deficiencies (PADs) are the most common form of primary
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …
Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets
CS Ma, N Wong, G Rao, A Nguyen, DT Avery… - Journal of Experimental …, 2016 - rupress.org
Naive CD4+ T cells differentiate into specific effector subsets—Th1, Th2, Th17, and T
follicular helper (Tfh)—that provide immunity against pathogen infection. The signaling …
follicular helper (Tfh)—that provide immunity against pathogen infection. The signaling …