NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review

JE Gutierrez-Virgen, M Pina-Pozas… - PLoS …, 2023 - journals.plos.org
Arylamine N-acetyltransferase 2 has been related to drug side effects and cancer
susceptibility; its protein structure and acetylation capacity results from the polymorphism's …

Dysregulation of microRNA modulatory network in abdominal aortic aneurysm

DP Zalewski, KP Ruszel, A Stępniewski… - Journal of Clinical …, 2020 - mdpi.com
Abdominal artery aneurysm (AAA) refers to abdominal aortic dilatation of 3 cm or greater.
AAA is frequently underdiagnosed due to often asymptomatic character of the disease …

Effects of major lifestyle factors on breast cancer risk: impact of weight, nutrition, physical activity, alcohol and tobacco

S Vegunta, SP Lester, S Pruthi… - Breast Cancer …, 2020 - Taylor & Francis
Breast cancer (BC) is the most commonly diagnosed cancer and second most common
cause of cancer death in US women. Family history and genetics are well-known BC risk …

Assessment of cancer embryonic antigen (CEA) biomarker in women with breast cancer disease

ZM AL-Nafakh, AN AL-Dujaili… - AIP Conference …, 2020 - pubs.aip.org
Breast cancer (BC) is the second close frequent most cancers among women, afterwards
pores and skin cancer. It is near typically determined of ladies used fifty five in conformity …

AKR1C2 genetic variants mediate tobacco carcinogens metabolism involving bladder cancer susceptibility

Y Xiao, Y Shen, H Song, F Gao, Z Mao, Q Lv, C Qin… - Archives of …, 2024 - Springer
Tobacco carcinogens metabolism-related genes (TCMGs) could generate reactive
metabolites of tobacco carcinogens, which subsequently contributed to multiple diseases …

A functional variant of the miR-15 family is associated with a decreased risk of esophageal squamous cell carcinoma

Y Shao, X Guo, L Zhao, Y Shen, C Niu, W Wei… - DNA and Cell …, 2020 - liebertpub.com
MicroRNAs (miRNAs)-related single-nucleotide polymorphisms (SNPs) have been shown to
be implicated in the susceptibility to different types of cancer, including esophageal …

Genetic variations in cytochrome P450 1A1 and 1B1 genes in a cohort of patients from Iraq diagnosed with breast cancer

SQ Ibrahem, HQ Ahmed… - Breast Cancer: Basic and …, 2021 - journals.sagepub.com
Breast cancer is the most prevalent malignant neoplasm in females. Genetic variations in the
xenobiotic metabolising cytochrome enzymes; Family 1 Subfamily A Member 1 (CYP1A1) …

Synergistic polymorphic interactions of phase II metabolizing genes and their association toward lung cancer susceptibility in North Indians

HK Walia, P Sharma, N Singh… - International Journal of …, 2024 - Taylor & Francis
Lung cancer is a multifactorial carcinoma with diverse heterogeneity. Genetic variations in
drug-metabolizing enzymes may lead to defective detoxification and clearance of …

Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers

AB Khan, R Patel, MF McDonald, E Goethe… - Journal of Neuro …, 2023 - Springer
Introduction Meningiomas are the most common primary intracranial tumor. Recently,
various genetic classification systems for meningioma have been described. We sought to …

Hypomethylation of AHRR (cg05575921) Is Related to Smoking Status in the Mexican Mestizo Population

OA Bravo-Gutiérrez, R Falfán-Valencia… - Genes, 2021 - mdpi.com
Tobacco smoking results in a multifactorial disease involving environmental and genetic
factors; epigenome-wide association studies (EWAS) show changes in DNA methylation …