[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …

Recent advances in pre-conditioned mesenchymal stem/stromal cell (MSCs) therapy in organ failure; a comprehensive review of preclinical studies

MS Kahrizi, E Mousavi, A Khosravi, S Rahnama… - Stem cell research & …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs)‐based therapy brings the reassuring capability to
regenerative medicine through their self‐renewal and multilineage potency. Also, they …

Role of Nrf2 in synaptic plasticity and memory in Alzheimer's disease

DA Davies, A Adlimoghaddam, BC Albensi - Cells, 2021 - mdpi.com
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important transcription factor that
reduces oxidative stress. When reactive oxygen species (ROS) or reactive nitrogen species …

[HTML][HTML] HIF-1α activator DMOG inhibits alveolar bone resorption in murine periodontitis by regulating macrophage polarization

M Chen, Y Wang, B Sun, L Yu, Q Chen, X Han… - International …, 2021 - Elsevier
Periodontitis is initiated by serious and sustained bacterial infection and ultimately results in
chronic immune-mediated inflammation, tissue destruction, and bone loss. The …

Stem cell therapy for Alzheimer's disease: An overview of experimental models and reality

C Qin, K Wang, L Zhang, L Bai - Animal models and …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disorder. The pathology of AD is
characterized by extracellular amyloid beta (Aβ) plaques, neurofibrillary tangles composed …

The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: crosstalk between autophagy …

C Qin, L Bai, Y Li, K Wang - Stem cell research & therapy, 2022 - Springer
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

Mesenchymal stem cell-and extracellular vesicle-based therapies for Alzheimer's disease: progress, advantages, and challenges

RG de Jesus Gonçalves, JF Vasques… - Neural Regeneration …, 2023 - journals.lww.com
Alzheimer's disease is a severe, highly disabling neurodegenerative disease, clinically
characterized by a progressive decline in cognitive functions, and is the most common form …

Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicine

M Adelipour, DM Lubman, J Kim - Expert opinion on biological …, 2023 - Taylor & Francis
Introduction Regenerative medicine involves the replacement of damaged cells, tissues, or
organs to restore normal function. Mesenchymal stem cells (MSCs) and exosomes secreted …

Genetic modification and preconditioning strategies to enhance functionality of mesenchymal stromal cells: a clinical perspective

K Moeinabadi-Bidgoli, R Mazloomnejad… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Mesenchymal stromal cell (MSC)-based therapy has generated great hope for
the treatment of various diseases such as myocardial infarction and stroke. Unfortunately …

Functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: inhibition of neuroinflammation

C Qin, Y Li, K Wang - Journal of inflammation research, 2021 - Taylor & Francis
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …