The lactoferrin phenomenon—a miracle molecule

P Kowalczyk, K Kaczyńska, P Kleczkowska… - Molecules, 2022 - mdpi.com
Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

Fluorescence sensing technologies for ophthalmic diagnosis

Y Shi, Y Hu, N Jiang, AK Yetisen - ACS sensors, 2022 - ACS Publications
Personalized and point-of-care (POC) diagnoses are critical for ocular physiology and
disease diagnosis. Real-time monitoring and continuous sampling abilities of tear fluid and …

Development of lactoferrin-loaded liposomes for the management of dry eye disease and ocular inflammation

A López-Machado, N Díaz-Garrido, A Cano, M Espina… - Pharmaceutics, 2021 - mdpi.com
Dry eye disease (DED) is a high prevalent multifactorial disease characterized by a lack of
homeostasis of the tear film which causes ocular surface inflammation, soreness, and visual …

Design and development of nanomaterial-based drug carriers to overcome the blood–brain barrier by using different transport mechanisms

J Song, C Lu, J Leszek, J Zhang - International Journal of Molecular …, 2021 - mdpi.com
Central nervous system (CNS) diseases are the leading causes of death and disabilities in
the world. It is quite challenging to treat CNS diseases efficiently because of the blood–brain …

Lipopolysaccharide of Legionella pneumophila Serogroup 1 Facilitates Interaction with Host Cells

B Kowalczyk, M Petzold, Z Kaczyński… - International Journal of …, 2023 - mdpi.com
Legionella pneumophila is the primary causative agent of Legionnaires' disease. The
mutant-type strain interrupted in the ORF7 gene region responsible for the …

[HTML][HTML] Smartphone-based fluorescent sensing platforms for point-of-care ocular lactoferrin detection

Y Shi, Y Zhang, Y Hu, R Moreddu, Z Fan… - Sensors and Actuators B …, 2023 - Elsevier
Lactoferrin is a critical glycoprotein that accounts for the major component in tear protein
composition. Tear lactoferrin has been indicated as a potential biomarker in ocular health …

Rapid detection of tear lactoferrin for diagnosis of dry eyes by using fluorescence polarization-based aptasensor

Y Zhang, P Yan, H Tang, J Zhang - Scientific Reports, 2023 - nature.com
Differentiating dry eye disease (DED) from allergic or viral conjunctivitis rapidly and
accurately is important to ensure prompt diagnosis and treatment. Tear lactoferrin (LF), a …

Tear biomarkers and Alzheimer's Disease

S Kaštelan, M Braš, N Pjevač, I Bakija, Z Tomić… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is an age-related progressive neurodegenerative brain disorder
that represents the most common type of dementia. It poses a significant diagnostic …

Salivary Biomarkers for Alzheimer's Disease: A Systematic Review with Meta-Analysis

K Nijakowski, W Owecki, J Jankowski… - International Journal of …, 2024 - mdpi.com
Alzheimer's Disease (AD) is the most common neurodegenerative disease which manifests
with progressive cognitive impairment, leading to dementia. Considering the noninvasive …

[HTML][HTML] Is liquid biopsy mature enough for the diagnosis of Alzheimer's disease?

X Gong, H Zhang, X Liu, Y Liu, J Liu… - Frontiers in Aging …, 2022 - frontiersin.org
The preclinical diagnosis and clinical practice for Alzheimer's disease (AD) based on liquid
biopsy have made great progress in recent years. As liquid biopsy is a fast, low-cost, and …