[HTML][HTML] Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system
Radiotherapy is a primary therapeutic modality widely utilized with curative intent.
Traditionally tumor response was hypothesized to be due to high levels of cell death …
Traditionally tumor response was hypothesized to be due to high levels of cell death …
The hallmarks of mathematical oncology
JA Bull, HM Byrne - Proceedings of the IEEE, 2022 - ieeexplore.ieee.org
Over the past 25 years, there has been an unparalleled increase in understanding of cancer
biology. This transformation is exemplified by Hanahan and Weinberg's decision in 2011 to …
biology. This transformation is exemplified by Hanahan and Weinberg's decision in 2011 to …
[HTML][HTML] Forecasting individual patient response to radiation therapy in head and neck cancer with a dynamic carrying capacity model
Purpose: In order for radiotherapy to enter the realm of personalized medicine it will be
necessary to model and predict individual patient responses to radiotherapy. Methods and …
necessary to model and predict individual patient responses to radiotherapy. Methods and …
Mathematical modelling of the dynamics of image-informed tumor habitats in a murine model of glioma
Tumors exhibit high molecular, phenotypic, and physiological heterogeneity. In this effort, we
employ quantitative magnetic resonance imaging (MRI) data to capture this heterogeneity …
employ quantitative magnetic resonance imaging (MRI) data to capture this heterogeneity …
A mathematical model of breast tumor progression based on immune infiltration
Breast cancer is the most prominent type of cancer among women. Understanding the
microenvironment of breast cancer and the interactions between cells and cytokines will …
microenvironment of breast cancer and the interactions between cells and cytokines will …
Modelling the Tumour Microenvironment, but What Exactly Do We Mean by “Model”?
CC Reyes-Aldasoro - Cancers, 2023 - mdpi.com
Simple Summary The word “model” can be used with different meanings and different
contexts, like a model student, clay models or a model railway. In some cases, the context …
contexts, like a model student, clay models or a model railway. In some cases, the context …
Data driven mathematical model of colon cancer progression
Every colon cancer has its own unique characteristics, and therefore may respond differently
to identical treatments. Here, we develop a data driven mathematical model for the …
to identical treatments. Here, we develop a data driven mathematical model for the …
[HTML][HTML] Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
We present a mathematical model that describes how tumour heterogeneity evolves in a
tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the …
tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the …
A framework for performing data-driven modeling of tumor growth with radiotherapy treatment
Recent technological advances make it possible to collect detailed information about
tumors, and yet clinical assessments about treatment responses are typically based on …
tumors, and yet clinical assessments about treatment responses are typically based on …
Simulating tumor volume dynamics in response to radiotherapy: Implications of model selection
From the beginning of the usage of radiotherapy (RT) for cancer treatment, mathematical
modeling has been integral to understanding radiobiology and for designing treatment …
modeling has been integral to understanding radiobiology and for designing treatment …