Influence of physicochemical properties of iron oxide nanoparticles on their antibacterial activity
The increasing occurrence of infectious diseases caused by antimicrobial resistance
organisms urged the necessity to develop more potent, selective, and safe antimicrobial …
organisms urged the necessity to develop more potent, selective, and safe antimicrobial …
Improving normothermic machine perfusion and blood transfusion through biocompatible blood silicification
The growing world population and increasing life expectancy are driving the need to
improve the quality of blood transfusion, organ transplantation, and preservation. Here, to …
improve the quality of blood transfusion, organ transplantation, and preservation. Here, to …
Biomechanics of phagocytosis of red blood cells by macrophages in the human spleen
The clearance of senescent and altered red blood cells (RBCs) in the red pulp of the human
spleen involves sequential processes of prefiltration, filtration, and postfiltration. While prior …
spleen involves sequential processes of prefiltration, filtration, and postfiltration. While prior …
How the spleen reshapes and retains young and old red blood cells: A computational investigation
The spleen, the largest secondary lymphoid organ in humans, not only fulfils a broad range
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …
of immune functions, but also plays an important role in red blood cell's (RBC) life cycle …
Single-cell characterization of deformation and dynamics of mesenchymal stem cells in microfluidic systems: A computational study
Understanding the homing dynamics of individual mesenchymal stem cells (MSCs) in
physiologically relevant microenvironments is crucial for improving the efficacy of MSC …
physiologically relevant microenvironments is crucial for improving the efficacy of MSC …
Computational investigation of flow dynamics and mechanical retention of age-associated red blood cells in the spleen
Red blood cells (RBCs) change shape and deformability with age, making them more likely
to be trapped in the splenic slits (IESs) and removed from circulation. Existing evidence …
to be trapped in the splenic slits (IESs) and removed from circulation. Existing evidence …
Physical mechanisms of red blood cell splenic filtration
A Moreau, F Yaya, H Lu… - Proceedings of the …, 2023 - National Acad Sciences
The splenic interendothelial slits fulfill the essential function of continuously filtering red
blood cells (RBCs) from the bloodstream to eliminate abnormal and aged cells. To date, the …
blood cells (RBCs) from the bloodstream to eliminate abnormal and aged cells. To date, the …
In silico and in vitro study of the adhesion dynamics of erythrophagocytosis in sickle cell disease
Erythrophagocytosis occurring in the spleen is a critical process for removing senescent and
diseased red blood cells (RBCs) from the microcirculation. Although some progress has …
diseased red blood cells (RBCs) from the microcirculation. Although some progress has …
Quantifying shear-induced margination and adhesion of platelets in microvascular blood flow
Platelet margination and adhesion are two critical and closely related steps in thrombus
formation. Using dissipative particle dynamics (DPD) method that seamlessly models blood …
formation. Using dissipative particle dynamics (DPD) method that seamlessly models blood …
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics
The spleen constantly clears altered red blood cells (RBCs) from the circulation, tuning the
balance between RBC formation (erythropoiesis) and removal. The retention and …
balance between RBC formation (erythropoiesis) and removal. The retention and …