The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

The blood–brain barrier (BBB) is a highly regulated physical and functional boundary that
tightly controls the transport of materials between the blood and the brain. There is an …

Blood-brain barrier (BBB) serves as an essential interface between central nervous system
(CNS) and its periphery, allowing selective permeation of ions, gaseous molecules, and …

In the 20th century, the discovery of antibiotics played an essential role in the fight against
infectious diseases, including meningitis, typhoid fever, pneumonia and Mycobacterium …

Although many pharmaceuticals have therapeutic potentials for central nervous system
(CNS) diseases, few of these agents have been effectively administered. It is due to the fact …

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease caused by the
deposition of amyloid β (Aβ) fibrils forming extracellular plaques and the development of …

As the search for modalities to cure Alzheimer's disease (AD) has made slow progress,
research has now turned to innovative pathways involving neural and peripheral …

Over the past decades, peptides and proteins have been increasingly important in the
treatment of various human diseases and conditions owing to their specificity, potency, and …

Alzheimer's disease (AD) is the most common form of dementia, with a high impact
worldwide, accounting for more than 46 million cases. The continuous increase of AD …

Parkinson's disease (PD) has significantly affected a large proportion of the elderly
population worldwide. According to the World Health Organization, approximately 8.5 million …