Bright Side of Fusarium oxysporum: Secondary Metabolites Bioactivities and Industrial Relevance in Biotechnology and Nanotechnology

SRM Ibrahim, A Sirwi, BG Eid, SGA Mohamed… - Journal of Fungi, 2021 - mdpi.com
Fungi have been assured to be one of the wealthiest pools of bio-metabolites with
remarkable potential for discovering new drugs. The pathogenic fungi, Fusarium oxysporum …

[HTML][HTML] Natural blue pigments and bikaverin

MC Dos Santos, JL Bicas - Microbiological Research, 2021 - Elsevier
In last years, the main studied microbial sources of natural blue pigments have been the
eukaryotic algae, Rhodophytes and Cryptophytes, and the cyanobacterium Arthrospira …

Pathway engineering in yeast for synthesizing the complex polyketide bikaverin

M Zhao, Y Zhao, M Yao, H Iqbal, Q Hu, H Liu… - Nature …, 2020 - nature.com
Fungal polyketides display remarkable structural diversity and bioactivity, and therefore the
biosynthesis and engineering of this large class of molecules is therapeutically significant …

How to completely squeeze a fungus—advanced genome mining tools for novel bioactive substances

A Schüller, L Studt-Reinhold, J Strauss - Pharmaceutics, 2022 - mdpi.com
Fungal species have the capability of producing an overwhelming diversity of bioactive
substances that can have beneficial but also detrimental effects on human health. These so …

Two separate key enzymes and two pathway‐specific transcription factors are involved in fusaric acid biosynthesis in Fusarium fujikuroi

L Studt, S Janevska, EM Niehaus… - Environmental …, 2016 - Wiley Online Library
Fusaric acid (FSA) is a mycotoxin produced by several fusaria, including the rice pathogen F
usarium fujikuroi. Genes involved in FSA biosynthesis were previously identified as a cluster …

Bioinformatic Analysis of Secondary Metabolite Biosynthetic Potential in Pathogenic Fusarium

C Lin, X Feng, Y Liu, Z Li, XZ Li, J Qi - Journal of Fungi, 2023 - mdpi.com
Fusarium species are among the filamentous fungi with the most pronounced impact on
agricultural production and human health. The mycotoxins produced by pathogenic …

Isolation of two novel purple naphthoquinone pigments concomitant with the bioactive red bikaverin and derivates thereof produced by Fusarium oxysporum

J Lebeau, T Petit, P Clerc, L Dufossé… - Biotechnology …, 2019 - Wiley Online Library
Filamentous fungi have gained growing interest as sources of diverse pigmented secondary
metabolites. Some specific polyketides from Ascomycetous species have demonstrated a …

Fungal gene cluster diversity and evolution

JC Slot - Advances in genetics, 2017 - Elsevier
Metabolic gene clusters (MGCs) have provided some of the earliest glimpses at the
biochemical machinery of yeast and filamentous fungi. MGCs encode diverse genetic …

Fusarium species—a promising tool box for industrial biotechnology

MG Pessôa, BN Paulino, MCR Mano… - Applied microbiology …, 2017 - Springer
Global demand for biotechnological products has increased steadily over the years. Thus,
need for optimized processes and reduced costs appear as a key factor in the success of …

Establishment of the Inducible Tet-On System for the Activation of the Silent Trichosetin Gene Cluster in Fusarium fujikuroi

S Janevska, B Arndt, L Baumann, LH Apken… - Toxins, 2017 - mdpi.com
The PKS-NRPS-derived tetramic acid equisetin and its N-desmethyl derivative trichosetin
exhibit remarkable biological activities against a variety of organisms, including plants and …