New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

ABSTRACT Introduction: Enterobacteriaceae, Pseudomonas spp., and Acinetobacter spp.
infections are major causes of morbidity and mortality, especially due to the emergence and …

Infants admitted to the neonatal intensive care unit, particularly those born preterm, are at
high risk for infection due to the combination of an immature immune system, prolonged …

The emergence and global spread of carbapenemase‐producing Enterobacteriaceae and
Acinetobacter baumannii are of great concern to health services worldwide. These β …

The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …

Organisms in the family Enterobactericeae including, Escherichia coli, commonly cause
community and hospital-associated infections in both humans and companion animals. The …

Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Enterobacter hormaechei, a member of the Enterobacter cloacae complex, has emerged as
an important pathogen in healthcare-associated infections. Advancements in phylogenetic …

New Delhi metallo-β-lactamase (NDM) carbapenemase has been considered a global
threat due to its worldwide widespread in recent years. In Portugal, a very low number of …