Omega‐6 (n‐6) polyunsaturated fatty acids (PUFA)(eg, arachidonic acid (AA)) and omega‐3
(n‐3) PUFA (eg, eicosapentaenoic acid (EPA)) are precursors to potent lipid mediator …

Lifestyle is a well-known environmental factor that plays a major role in facilitating the
development of metabolic syndrome or eventually exacerbating its consequences. Various …

Epidemiological studies on Greenland Inuits in the 1970s and subsequent human studies
have established an inverse relationship between the ingestion of omega-3 fatty acids [C 20 …

Fatty acid regulation of hepatic gene transcription was first reported in the early 1990s.
Several transcription factors have been identified as targets of fatty acid regulation. This …

Obesity is a pandemic disease associated with many metabolic alterations and involves
several organs and systems. The endocannabinoid system (ECS) appears to be a key …

Non-alcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. It
is the most important cause of chronic liver disease and a major independent cardiovascular …

Western diets are characterized by both dietary omega-3 fatty acid deficiency and increased
fructose intake. The latter found in high amounts in added sugars such as sucrose and high …

Growing evidence underscores the important role of glycemic control in health and recovery
from illness. Carbohydrate ingestion in the diet or administration in nutritional support is …

The potential role of endogenously synthesized PUFAs is a highly overlooked area.
Elongation of very long-chain fatty acids (ELOVLs) in mammals is catalyzed by the ELOVL …

Background Metabolic abnormalities are common in HIV-infected individuals on
antiretroviral therapy (ART), but the biochemical details and underlying mechanisms of …