One of the challenges in the Comparative Genomics field is to infer how close two
organisms are based on the similarities and differences between their genetic materials …

A comprehensive survey of a rapidly expanding field of combinatorial optimization,
mathematically oriented but offering biological explanations when required. From one cell to …

In comparative genomics, rearrangements are mutations that affect a stretch of DNA
sequences. Reversals and transpositions are well-known rearrangements, and each has a …

During the evolutionary process, genomes are affected by various genome rearrangements,
that is, events that modify large stretches of the genetic material. In the literature, a large …

The rearrangement distance is a well-known problem in the field of comparative genomics.
Given two genomes, the rearrangement distance is the minimum number of rearrangements …

The rearrangement distance is a method to compare genomes of different species. Such
distance is the number of rearrangement events necessary to transform one genome into …

Background In the comparative genomics field, one of the goals is to estimate a sequence of
genetic changes capable of transforming a genome into another. Genome rearrangement …

Recent works on genome rearrangements have shown that incorporating intergenic region
information along with gene order in models provides better estimations for the …

Genome rearrangements are global mutations that change large stretches of DNA sequence
throughout genomes. They are rare but accumulate during the evolutionary process leading …

Background During evolution, global mutations may alter the order and the orientation of the
genes in a genome. Such mutations are referred to as rearrangement events, or simply …