Imaging vascular and hemodynamic features of the brain using dynamic susceptibility contrast and dynamic contrast enhanced MRI

CC Quarles, LC Bell, AM Stokes - Neuroimage, 2019 - Elsevier
In the context of neurologic disorders, dynamic susceptibility contrast (DSC) and dynamic
contrast enhanced (DCE) MRI provide valuable insights into cerebral vascular function …

[HTML][HTML] Single-shot multi-parametric mapping based on multiple overlapping-echo detachment (MOLED) imaging

L Ma, J Wu, Q Yang, Z Zhou, H He, J Bao, L Bao… - Neuroimage, 2022 - Elsevier
Multi-parametric quantitative magnetic resonance imaging (mqMRI) allows the
characterization of multiple tissue properties non-invasively and has shown great potential …

Concurrent measurement of perfusion parameters related to small blood vessels and cerebrospinal fluid circulation in the human brain using dynamic dual‐spin‐echo …

D Cao, Y Sun, Y Li, P Su, JJ Pillai, Y Qiao… - NMR in …, 2023 - Wiley Online Library
Accumulating evidence from recent studies has indicated the importance of studying the
interaction between the microvascular and lymphatic systems in the brain. To date, most …

[HTML][HTML] A population-based digital reference object (DRO) for optimizing dynamic susceptibility contrast (DSC)-MRI methods for clinical trials

NB Semmineh, AM Stokes, LC Bell… - …, 2017 - pmc.ncbi.nlm.nih.gov
The standardization and broad-scale integration of dynamic susceptibility contrast (DSC)-
magnetic resonance imaging (MRI) have been confounded by a lack of consensus on DSC …

Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients

AM Stokes, M Bergamino, L Alhilali… - Journal of Cerebral …, 2021 - journals.sagepub.com
Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC)
MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we …

Optimization of acquisition and analysis methods for clinical dynamic susceptibility contrast MRI using a population-based digital reference object

NB Semmineh, LC Bell, AM Stokes… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The accuracy of DSC-MR imaging CBV maps in
glioblastoma depends on acquisition and analysis protocols. Multisite protocol …

Optimization and validation of multi-echo, multi-contrast SAGE acquisition in fMRI

EG Keeling, M Bergamino, S Ragunathan… - Imaging …, 2024 - direct.mit.edu
The purpose of this study was to optimize and validate a multi-contrast, multi-echo fMRI
method using a combined spin-and gradient-echo (SAGE) acquisition. It was hypothesized …

Velocity-Selective Arterial Spin Labeling Perfusion in Monitoring High Grade Gliomas Following Therapy: Clinical Feasibility at 1.5 T and Comparison with Dynamic …

S Lambrecht, D Liu, O Dzaye, DO Kamson, J Reis… - Brain Sciences, 2024 - mdpi.com
MR perfusion imaging is important in the clinical evaluation of primary brain tumors,
particularly in differentiating between true progression and treatment-induced change. The …

Development of a spiral spin‐and gradient‐echo (spiral‐SAGE) approach for improved multi‐parametric dynamic contrast neuroimaging

AM Stokes, S Ragunathan, RK Robison… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose The purpose of this study was to develop a spiral‐based combined spin‐and
gradient‐echo (spiral‐SAGE) method for simultaneous dynamic contrast‐enhanced (DCE …

Assessment of a simplified spin and gradient echo (sSAGE) approach for human brain tumor perfusion imaging

AM Stokes, JT Skinner, T Yankeelov… - Magnetic resonance …, 2016 - Elsevier
The goal of this study was to validate a simplified spin-and gradient-echo (sSAGE) approach
to obtain T 1-corrected dynamic susceptibility contrast magnetic resonance imaging (DSC …