Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association

RD Brook, S Rajagopalan, CA Pope III, JR Brook… - Circulation, 2010 - Am Heart Assoc
In 2004, the first American Heart Association scientific statement on “Air Pollution and
Cardiovascular Disease” concluded that exposure to particulate matter (PM) air pollution …

Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Macrophages and tissue injury: agents of defense or destruction?

DL Laskin, VR Sunil, CR Gardner… - Annual review of …, 2011 - annualreviews.org
The past several years have seen the accumulation of evidence demonstrating that tissue
injury induced by diverse toxicants is due not only to their direct effects on target tissues but …

Nanoparticle emissions from 11 non-vehicle exhaust sources–a review

P Kumar, L Pirjola, M Ketzel, RM Harrison - Atmospheric Environment, 2013 - Elsevier
Nanoparticle emissions from road vehicles have been studied extensively in the recent past
due to their dominant contribution towards the total airborne particle number concentrations …

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

A Nemmar, JA Holme, I Rosas… - BioMed research …, 2013 - Wiley Online Library
Epidemiological and clinical studies have linked exposure to particulate matter (PM) to
adverse health effects, which may be registered as increased mortality and morbidity from …

Activation of proinflammatory responses in cells of the airway mucosa by particulate matter: oxidant-and non-oxidant-mediated triggering mechanisms

J Øvrevik, M Refsnes, M Låg, JA Holme, PE Schwarze - Biomolecules, 2015 - mdpi.com
Inflammation is considered to play a central role in a diverse range of disease outcomes
associated with exposure to various types of inhalable particulates. The initial mechanisms …

Role of oxidative damage in toxicity of particulates

P Møller, NR Jacobsen, JK Folkmann… - Free radical …, 2010 - Taylor & Francis
Particulates are small particles of solid or liquid suspended in liquid or air. In vitro studies
show that particles generate reactive oxygen species, deplete endogenous antioxidants …

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

R Miyata, SF van Eeden - Toxicology and applied pharmacology, 2011 - Elsevier
Emerging epidemiological evidence suggests that exposure to particulate matter (PM) air
pollution increases the risk of cardiovascular events but the exact mechanism by which PM …

Epidemiological and experimental links between air pollution and type 2 diabetes

C Liu, Z Ying, J Harkema, Q Sun… - Toxicologic …, 2013 - journals.sagepub.com
There is increasing evidence suggesting links between exposure to environmental toxins
and susceptibility to type 2 diabetes mellitus (DM). In this review, we summarize the …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …