Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical
interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast …

The global malaria burden sometimes obscures that the genus Plasmodium comprises
diverse clades with lineages that independently gave origin to the extant human parasites …

The most severe form of malaria is caused by Plasmodium falciparum. These parasites
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …

The symptoms of malaria occur during the blood stage of infection, when parasites invade
and replicate within human erythrocytes. The PfPCRCR complex, containing PfRH5 (refs.,) …

Despite ongoing efforts, a highly effective vaccine against Plasmodium falciparum remains
elusive. Vaccines targeting the pre-erythrocytic stages of the P. falciparum life cycle are the …

Plasmodium vivax is responsible for most of the malaria infections outside Africa and is
currently the predominant malaria parasite in countries under elimination programs. P. vivax …

Many important infectious diseases are the result of zoonoses, in which pathogens that
normally infect animals acquire mutations that enable the breaching of species barriers to …

Background The population history of Plasmodium simium, which causes malaria in sylvatic
Neotropical monkeys and humans along the Atlantic Coast of Brazil, remains disputed …

Plasmodium malaria parasites are obligate intracellular protozoans that use a unique form
of locomotion, termed gliding motility, to move through host tissues and invade cells. The …

Apicomplexa are obligate intracellular parasites. While most species are restricted to
specific hosts and cell types, Toxoplasma gondii can invade every nucleated cell derived …