Acute fatty liver of pregnancy (AFLP) is an obstetric emergency characterized by maternal
liver failure and may have complications for the mother and fetus, including death. This …

A frequent mechanism for drug-induced liver injury (DILI) is the formation of reactive
metabolites that trigger hepatitis through direct toxicity or immune reactions. Both events …

Liver diseases in pregnancy comprise both gestational liver disorders and acute and chronic
hepatic disorders occurring coincidentally in pregnancy. Whether related to pregnancy or …

Hepatic steatosis defined as lipid accumulation in hepatocytes is very frequently found in
adults and obese adolescents in the Western World. Etiologically, obesity and associated …

The liver disorders unique to pregnancy include hyperemesis gravidarum, intrahepatic
cholestasis of pregnancy, acute fatty liver of pregnancy, and preeclampsia-associated …

Low-income and middle-income countries have historically struggled to provide access to
anesthesia and surgical services for their patient populations, but this is also a difficulty for …

Preeclampsia is a multisystemic disorder which accounts for the high prevalence of maternal
and perinatal morbidity and mortality, especially in middle and low-income countries …

Liver disorders occurring during pregnancy may be specifically pregnancy-related, or may
be due to an intercurrent or chronic liver disease, which may present in anyone, pregnant or …

The liver is one of the richest organs in mitochondria, serving as a hub for key metabolic
pathways such as β-oxidation, the tricarboxylic acid (TCA) cycle, ketogenesis, respiratory …

Pregnancy-related liver disorders accounted for 8% of all maternal deaths at our center from
1999 to 2011. Of the three pregnancy-related liver disorders (acute fatty liver of pregnancy …