Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties

M Boztas, Y Cetinkaya, M Topal, I Gulcin… - Journal of medicinal …, 2015 - ACS Publications
Cyclopropylcarboxylic acids and esters and cyclopropylmethanols incorporating
bromophenol moieties were investigated as inhibitors of the carbonic anhydrase enzyme …

Unexpected regioselectivity observed in the bromination and epoxidation reactions of p-benzoquinone-fused norbornadiene: An experimental and computational …

S Essiz, E Dalkilic, O Sari, A Dastan, M Balci - Tetrahedron, 2017 - Elsevier
The bromination reaction of p-benzoquinone-fused norbornadiene was studied at various
temperatures (− 78,− 50, 0, 25, and 77° C). At room temperature, the double bonds of the p …

Unusual manganese (III)-mediated oxidative free radical additions of 1, 3-dicarbonyl compounds to benzonorbornadiene and 7-heterobenzonorbornadienes …

R Çalışkan, MF Ali, E Şahin, WH Watson… - The Journal of Organic …, 2007 - ACS Publications
Benzonorbornadiene and heterobenzonorbornadiene were reacted with dimedone/
acetylacetone and Mn (OAc) 3 in the presence and absence of Cu (OAc) 2. The reaction of …

Bromination of norbornene derivatives: Synthesis of brominated norbornanes and norbornenes

DD Gültekin, Y Taşkesenligil, A Daştan, M Balci - Tetrahedron, 2008 - Elsevier
The low and high temperature bromination of 7-bromobicyclo [2.2. 1] hept-2-ene and 2, 7-
dibromobicyclo [2.2. 1] hept-2-ene were studied and the possible role of a neighboring …

Sequential Rearrangements and Unusual Isomerization with KOtBu: Synthesis of anti-12-Vinyltricyclo [6.3. 1.02, 7] dodeca-2, 4, 6, 9-tetraene and its Derivatives

A Menzek - Tetrahedron, 2000 - Elsevier
The reaction of alcohol 13a with SOCl2 gave 13b, 14a and 15a, and the reaction of chloride
13b with AgNO3 (in MeO−/MeOH) gave 13c, 14b and 15b. In these reactions, 14a, 14b, 15a …

High temperature bromination VIII: Bromination of homobenzonorbornadiene

A Daştan, Y TaŞkesenligil, F Tümer, M Balci - Tetrahedron, 1996 - Elsevier
The electrophilic addition of bromine to homobenzonorbornadiene (3) at 10° C led in
quantitative yield to the formation of di-anti-bromo adduct 4. However, high-temperature …

Synthesis and structure elucidation of bromination products from dibromohomobenzonorbornadienes: high temperature bromination—Part 17

C Kazaz, A Daştan, M Balcı - Magnetic Resonance in …, 2005 - Wiley Online Library
The electrophilic addition of bromine to dibromohomobenzonorbornadiene derivatives at−
45±5° C led to the formation of the rearranged and non‐rearranged tetrabromides in a ratio …

Synthesis of 2, 3-, 2, 5-, and 2, 6-disubstituted-benzobarrelenes high temperature bromination II

M Balci, O Çakmak, T Hokelek - Tetrahedron, 1992 - Elsevier
Bromination of 2-bromo-1, 4-dihydro-1, 4-ethenonaphthalene (7) at-0 0C has been found to
give five rearranged tribromides 8, 9, 10, 11, and 12 via Wagner-Meerwein rearrangement …

Bromination of benzobicyclic system with 1, 2-dibromotetracholoroethane: unusual radical rearrangement

A Dastan - Tetrahedron, 2001 - Elsevier
The bromination reaction of a benzobicyclic system with 1, 2-dibromotetracholoroethane
(DBTCE) was studied. For tricyclo [6.2. 2.02, 7] dodeca-2, 4, 6, 9, 11-pentaene, rearranged …

Manganese (III)-mediated oxidative free-radical additions of 1, 3-dicarbonyl compounds to homobenzonorbornadiene and benzobarrelene: mechanistic studies

MF Ali, R Çalışkan, E Şahin, M Balci - Tetrahedron, 2009 - Elsevier
Homobenzonorbornadiene and benzobarrelene were reacted with dimedone/acetylacetone
and Mn (OAc) 3 in the presence of Cu (OAc) 2 in acetic acid. Mainly rearranged products …