New concepts for an old problem: the diagnosis of endometrial hyperplasia

PA Sanderson, HOD Critchley… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Endometrial hyperplasia (EH) is a uterine pathology representing a
spectrum of morphological endometrial alterations. It is predominantly characterized by an …

High-grade endometrial carcinomas: morphologic and immunohistochemical features, diagnostic challenges and recommendations

R Murali, B Davidson, O Fadare… - International Journal …, 2019 - journals.lww.com
This review of challenging diagnostic issues concerning high-grade endometrial carcinomas
is derived from the authors' review of the literature followed by discussions at the …

The genetic landscape of endometrial clear cell carcinomas

DF DeLair, KA Burke, P Selenica, RS Lim… - The Journal of …, 2017 - Wiley Online Library
Clear cell carcinoma of the endometrium is a rare type of endometrial cancer that is
generally associated with an aggressive clinical behaviour. Here, we sought to define the …

New WHO classification of endometrial hyperplasias

G Emons, MW Beckmann, D Schmidt… - Geburtshilfe und …, 2015 - thieme-connect.com
Conclusion The new WHO classification represents an important simplification for clinical
practice, particularly with regard to the choice of treatment. Until the new classification …

New classification system of endometrial hyperplasia WHO 2014 and its clinical implications

K Sobczuk, A Sobczuk - Menopause Review/Przegląd Menopauzalny, 2017 - termedia.pl
Endometrial hyperplasia (EH) is a pathological condition characterised by hyperplastic
changes in endometrial glandular and stromal structures lining the uterine cavity …

Progesterone and endometrial cancer

A Gompel - Best practice & research Clinical obstetrics & …, 2020 - Elsevier
It is well established that unopposed estrogen, either endogenous or therapeutic, can
induce endometrial hyperplasia and potentially endometrial cancer (EC). Anovulatory …

Pathophysiology of heavy menstrual bleeding

DK Hapangama, JN Bulmer - Women's Health, 2016 - journals.sagepub.com
Heavy menstrual bleeding (HMB) is a common gynecological complaint with multiple
etiologies and diverse pathophysiological origins. This review discusses HMB with …

Fertility-sparing approaches in atypical endometrial hyperplasia and endometrial cancer patients: current evidence and future directions

NA Contreras, J Sabadell, P Verdaguer, C Julià… - International journal of …, 2022 - mdpi.com
Endometrial cancer (EC) is the fourth most common cancer in women in developed
countries. Although it is usually diagnosed in postmenopausal women, its incidence has …

[HTML][HTML] Issues in the differential diagnosis of uterine low-grade endometrioid carcinoma, including mixed endometrial carcinomas: recommendations from the …

JT Rabban, CB Gilks, A Malpica… - International Journal …, 2019 - journals.lww.com
This article provides practical recommendations developed from the International Society of
Gynecological Pathologists Endometrial Carcinoma Project to address 4 issues that may …

Clear cell carcinoma of the endometrium

G Bogani, I Ray-Coquard, N Concin, NYL Ngoi… - Gynecologic …, 2022 - Elsevier
Clear cell endometrial carcinoma represents an uncommon and poorly understood entity.
Data from molecular/genomic profiling highlighted the importance of various signatures in …