The past fifty years have seen the development and application of numerous statistical
methods to identify genomic regions that appear to be shaped by natural selection. These …

The ancient biological'arms race'between microbial pathogens and humans has shaped
genetic variation in modern populations, and this has important implications for the growing …

The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

Background For more than a decade, risk stratification for hypertrophic cardiomyopathy has
been enhanced by targeted genetic testing. Using sequencing results, clinicians routinely …

A scientist integrates evolutionary biology, genetics, psychology, economics, and more to
explore the development and workings of human societies.“There is no good reason why …

Transcriptional regulation and posttranscriptional processing underlie many cellular and
organismal phenotypes. We used RNA sequence data generated by Genotype-Tissue …

As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher …

Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the
extent of population differences in immune responses and their genetic and evolutionary …

NEW YORK TIMES BESTSELLER• The# 1 bestselling author of The Anxious Generation
and acclaimed social psychologist challenges conventional thinking about morality, politics …

Domesticated crops experience strong human-mediated selection aimed at developing high-
yielding varieties adapted to local conditions. To detect regions of the wheat genome subject …