MRG‐1 is required for both chromatin‐based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans

T Miwa, K Inoue, H Sakamoto - Genes to Cells, 2019 - Wiley Online Library
In Caenorhabditis elegans, germline cells remain transcriptionally silenced during
embryogenesis. The transcriptional silencing is achieved by two different mechanisms: One …

Understanding the Role of MRG-1 in C. Elegans Germline and Somatic Development

CA Doronio - 2022 - search.proquest.com
The chromatin structure formed by the packaging of DNA into nucleosomes greatly
influences the transcriptional regulation of genes. Histone modifications like acetylation and …

A Chromodomain Mutation Identifies Separable Roles for C. elegans MRG-1 in Germline and Somatic Development

CA Doronio, H Ling, EJ Gleason, WG Kelly - bioRxiv, 2022 - biorxiv.org
The packaging of DNA into chromatin strongly influences gene regulation. Post-translational
modifications of histones, and the proteins that bind to them, alter the accessibility of …