Purpose Metformin has been used clinically for more than six decades. Over time, numerous
remarkable effects of metformin beyond the clinic have been discovered and discussed …

Purpose Metastatic castration-resistant prostate cancer (mCRPC) is a lethal disease that
imposes a major burden on patients and healthcare systems. Three structured literature …

Conclusion In conclusion, the addition of enzalutamide to ADT has been demonstrated to be
effective in all the PC settings where it has been tested, and the latest data from the …

Despite being an important goal, the preservation of quality of life of patients with metastatic
castration-resistant prostate cancer (mCRPC) is poorly characterized across lines of therapy …

Background The benefits of novel androgen receptor axis-targeted agents (ARATs) on
oncological outcomes in patients with non-metastatic castration-resistant prostate cancer …

Abstract Objective To explore whether 68Ga-PSMA-11 PET/CT-derived parameters could
predict biochemical response to abiraterone acetate (AA) treatment and prognosis in …

Objective To investigate the predictive value of body composition parameters for
biochemical response to abiraterone acetate (AA) in metastatic castration‐resistant prostate …

Aim: This review aims to summarize published evidence on the real-world (RW) outcomes of
abiraterone or enzalutamide in first-line metastatic castration-resistant prostate cancer …

Background The objective of this study was to evaluate the background and treatment
course of patients with metastatic prostate cancer (PC), with a particular focus on …

It is well known that the role of gut microbiota in drug metabolism, especially in oral difficult
absorbable drugs. Understanding the gut microbiota could enable us to understand drugs in …