The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy

M Alizadeh, A Safarzadeh… - Journal of cellular …, 2019 - Wiley Online Library
Abstract miR‐29 family is one of the small noncoding RNAs and has a very important role in
many physiologic and pathologic functions through regulating the target genes that play …

Low-dose ionizing radiation exposure, oxidative stress and epigenetic programing of health and disease

S Tharmalingam, S Sreetharan… - Radiation …, 2017 - meridian.allenpress.com
Ionizing radiation exposure from medical diagnostic imaging has greatly increased over the
last few decades. Approximately 80% of patients who undergo medical imaging are …

[HTML][HTML] Re-evaluation of the linear no-threshold (LNT) model using new paradigms and modern molecular studies

S Tharmalingam, S Sreetharan, AL Brooks… - Chemico-Biological …, 2019 - Elsevier
The linear no-threshold (LNT) model is currently used to estimate low dose radiation (LDR)
induced health risks. This model lacks safety thresholds and postulates that health risks …

p53 target miR-29c-3p suppresses colon cancer cell invasion and migration through inhibition of PHLDB2

G Chen, T Zhou, Y Li, Z Yu, L Sun - Biochemical and Biophysical Research …, 2017 - Elsevier
Abstract miR-29c-3p is a potential tumor suppressor microRNA that is reportedly
downregulated in several types of human cancers, but its role in colon cancer remains to be …

[HTML][HTML] The role of PPM1D in cancer and advances in studies of its inhibitors

W Deng, J Li, K Dorrah, D Jimenez-Tapia… - Biomedicine & …, 2020 - Elsevier
A greater understanding of factors causing cancer initiation, progression and evolution is of
paramount importance. Among them, the serine/threonine phosphatase PPM1D, also …

Tumor suppressor miR-29c regulates radioresistance in lung cancer cells

E Arechaga-Ocampo, C Lopez-Camarillo… - Tumor …, 2017 - journals.sagepub.com
Radiotherapy is an important treatment option for non-small cell lung carcinoma patients.
Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of …

Downregulation of miR-29c-3p is associated with a poor prognosis in patients with laryngeal squamous cell carcinoma

R Fang, Y Huang, J Xie, J Zhang, X Ji - Diagnostic pathology, 2019 - Springer
Background Laryngeal squamous cell carcinoma (LSCC) is considered to be a common
malignancy of the head and neck with poor prognosis for its late diagnosis, metastasis and …

Differential expression of hsa-miR-221, hsa-miR-21, hsa-miR-135b, and hsa-miR-29c suggests a field effect in oral cancer

CB Lopes, LL Magalhães, CR Teófilo, APNN Alves… - BMC cancer, 2018 - Springer
Background The theory of field effect suggests that the tumor-adjacent area, besides
histopathologically normal, undergoes genetic and epigenetic changes that can eventually …

microRNA-29c inhibits cell proliferation by targeting NASP in human gastric cancer

B Yu, X Chen, J Li, Q Gu, Z Zhu, C Li, L Su, B Liu - BMC cancer, 2017 - Springer
Background Gastric cancer is one of the most common malignancies worldwide. Recent
studies have shown that microRNAs play crucial roles in regulating cellular proliferation …

[HTML][HTML] Genome wide profiling of miRNAs relevant to the DNA damage response induced by hexavalent chromium exposure (DDR-related miRNAs in response to Cr …

L Shi, L Feng, Y Tong, J Jia, T Li, J Wang, Z Jiang… - Environment …, 2021 - Elsevier
Aim We aimed to explore the expression of miRNAs and their potential roles in the DNA
damage response (DDR) induced by Cr (VI) exposure in human B lymphoblast cells (HMy2 …