The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases—Part III: In-silico molecular docking investigations
IV Ogungbe, WN Setzer - Molecules, 2016 - mdpi.com
Malaria, leishmaniasis, Chagas disease, and human African trypanosomiasis continue to
cause considerable suffering and death in developing countries. Current treatment options …
cause considerable suffering and death in developing countries. Current treatment options …
Membrane protein structure determination by SAD, SIR, or SIRAS phasing in serial femtosecond crystallography using an iododetergent
The 3D structure determination of biological macromolecules by X-ray crystallography
suffers from a phase problem: to perform Fourier transformation to calculate real space …
suffers from a phase problem: to perform Fourier transformation to calculate real space …
SAD phasing using iodide ions in a high-throughput structural genomics environment
J Abendroth, AS Gardberg, JI Robinson… - Journal of structural and …, 2011 - Springer
Abstract The Seattle Structural Genomics Center for Infectious Disease (SSGCID) focuses
on the structure elucidation of potential drug targets from class A, B, and C infectious …
on the structure elucidation of potential drug targets from class A, B, and C infectious …
[HTML][HTML] Structure-function relationship of H2A-H2B specific plant histone chaperones
A Kumar, D Vasudevan - Cell Stress and Chaperones, 2020 - Elsevier
Studies on chromatin structure and function have gained a revived popularity. Histone
chaperones are significant players in chromatin organization. They play a significant role in …
chaperones are significant players in chromatin organization. They play a significant role in …
Characterization of Caenorhabditis elegans Nucleosome Assembly Protein 1 Uncovers the Role of Acidic Tails in Histone Binding
P Sarkar, N Zhang, S Bhattacharyya, K Salvador… - Biochemistry, 2018 - ACS Publications
Nucleosome assembly proteins (Naps) influence chromatin dynamics by directly binding to
histones. Here we provide a comprehensive structural and biochemical analysis of a Nap …
histones. Here we provide a comprehensive structural and biochemical analysis of a Nap …
Parallel evolution of chemokine binding by structurally related herpesvirus decoy receptors
OY Lubman, DH Fremont - Structure, 2016 - cell.com
A wide variety of pathogens targets chemokine signaling networks in order to disrupt host
immune surveillance and defense. Here, we report a structural and mutational analysis of …
immune surveillance and defense. Here, we report a structural and mutational analysis of …
Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum
Abstract Background Nucleosome assembly proteins (NAPs) are histone chaperones that
are crucial for the shuttling and incorporation of histones into nucleosomes. NAPs participate …
are crucial for the shuttling and incorporation of histones into nucleosomes. NAPs participate …
Utility of anion and cation combinations for phasing of protein structures
We report the use of anionic (I−), cationic (Ba 2+, Cd 2+) and ionic mixtures (I− plus Ba 2+)
for derivatizing liver fatty acid binding protein (LFABP) crystals. Use of cationic and anionic …
for derivatizing liver fatty acid binding protein (LFABP) crystals. Use of cationic and anionic …
Structure of d-tyrosyl-tRNATyr deacylase using home-source Cu Kα and moderate-quality iodide-SAD data: structural polymorphism and HEPES-bound enzyme …
d-Tyrosyl-tRNATyr deacylase (DTD) is an editing enzyme that removes d-amino acids from
mischarged tRNAs. The crystal structure of Plasmodium falciparum DTD (PfDTD) was …
mischarged tRNAs. The crystal structure of Plasmodium falciparum DTD (PfDTD) was …
In-house zinc SAD phasing at Cu Kα edge
MK Kim, S Lee, YJ An, CS Jeong, CJ Ji, JW Lee… - Molecules and …, 2013 - Springer
De novo zinc single-wavelength anomalous dispersion (Zn-SAD) phasing has been
demonstrated with the 1.9 Å resolution data of glucose isomerase and 2.6 Å resolution data …
demonstrated with the 1.9 Å resolution data of glucose isomerase and 2.6 Å resolution data …