Transient receptor potential channels: current perspectives on evolution, structure, function and nomenclature
The transient receptor potential superfamily of ion channels (TRP channels) is widely
recognized for the roles its members play in sensory nervous systems. However, the …
recognized for the roles its members play in sensory nervous systems. However, the …
Evolution of sensory receptors
WA Valencia-Montoya, NE Pierce… - Annual review of cell …, 2024 - annualreviews.org
Sensory receptors are at the interface between an organism and its environment and thus
represent key sites for biological innovation. Here, we survey major sensory receptor …
represent key sites for biological innovation. Here, we survey major sensory receptor …
Evolution of mechanisms and behaviour important for pain
ET Walters, ACC Williams - Philosophical Transactions of …, 2019 - royalsocietypublishing.org
Our understanding of the biology of pain is limited by our ignorance about its evolution. We
know little about how states in other species showing various degrees of apparent similarity …
know little about how states in other species showing various degrees of apparent similarity …
Evidence that the cold-and menthol-sensing functions of the human TRPM8 channel evolved separately
Transient receptor potential melastatin 8 (TRPM8) is a temperature-and menthol-sensitive
ion channel that contributes to diverse physiological roles, including cold sensing and pain …
ion channel that contributes to diverse physiological roles, including cold sensing and pain …
Regulation of the antennal transcriptome of the dengue vector, Aedes aegypti, during the first gonotrophic cycle
Background In the light of dengue being the fastest growing transmissible disease, there is a
dire need to identify the mechanisms regulating the behaviour of the main vector Aedes …
dire need to identify the mechanisms regulating the behaviour of the main vector Aedes …
Phylogenetics identifies two eumetazoan TRPM clades and an eighth TRP family, TRP soromelastatin (TRPS)
Transient receptor potential melastatins (TRPMs) are most well known as cold and menthol
sensors, but are in fact broadly critical for life, from ion homeostasis to reproduction. Yet, the …
sensors, but are in fact broadly critical for life, from ion homeostasis to reproduction. Yet, the …
Chloride-dependent mechanisms of multimodal sensory discrimination and nociceptive sensitization in Drosophila
Individual sensory neurons can be tuned to many stimuli, each driving unique, stimulus-
relevant behaviors, and the ability of multimodal nociceptor neurons to discriminate between …
relevant behaviors, and the ability of multimodal nociceptor neurons to discriminate between …
Formin 3 directs dendritic architecture via microtubule regulation and is required for somatosensory nociceptive behavior
Dendrite shape impacts functional connectivity and is mediated by organization and
dynamics of cytoskeletal fibers. Identifying the molecular factors that regulate dendritic …
dynamics of cytoskeletal fibers. Identifying the molecular factors that regulate dendritic …
TRPA1-mediated repellency behavior in the red flour beetle Tribolium castaneum
K Shimomura, S Ino, K Tamura, T Terajima… - Scientific Reports, 2022 - nature.com
The sensory perception of irritant chemicals results in escape and repellency behavioral
patterns in insects. Transient receptor potential channels are cation channels that function …
patterns in insects. Transient receptor potential channels are cation channels that function …
Distinct relations of microtubules and actin filaments with dendritic architecture
Microtubules (MTs) and F-actin (F-act) have long been recognized as key regulators of
dendritic morphology. Nevertheless, precisely ascertaining their distinct influences on …
dendritic morphology. Nevertheless, precisely ascertaining their distinct influences on …