While many efforts have been made to pave the way toward human space colonization, little
consideration has been given to the methods of protecting spacefarers against harsh cosmic …

There has been a significant increase in the incidence of multiple neurodegenerative and
terminal diseases in the human population with life expectancy increasing in the current …

Research on aging and lifespan-extending compounds has been carried out using diverse
model organisms, including yeast, worms, flies and mice. Many studies reported the …

Epicatechin (EC), a flavonoid present in various foods including cocoa, dark chocolate,
berries, and tea, has recently been reported to promote general health and survival of old …

Humans and other organisms show age-related signs of deterioration, which makes aging
an interesting process to study. In the present work, we review the anti-aging evidence of …

The gradual ageing of the world population has been accompanied by a dramatic increase
in the prevalence of obesity and metabolic diseases, especially type 2 diabetes. The …

Withanolides are a class of compounds usually found in plant extracts which are an
attractive geroprotective drug design starting point. We evaluated the geroprotective …

As the molecular mechanisms of biological aging become better understood, there is
growing interest in identifying interventions that target those mechanisms to promote …

Growing evidence suggests that a flavonoid-rich diet can prevent or reverse the effects of
stressors, although the underlying mechanisms remain poorly understood. One common …

Iron is an essential metal involved in several biological processes ranging from the transport
of oxygen to energy production and DNA synthesis. It is important for mitochondrial function …