Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

The increasing prevalence of antibacterial resistance globally underscores the urgent need
to the update of antibiotics. Here, we describe a strategy for inducing the self-assembly of a …

In recent years, the increase of invasive fungal infections and the emergence of antifungal
resistance stressed the need for new antifungal drugs. Peptides have shown to be good …

Due to the emergence of reports of multidrug-resistant fungi, infections caused by multidrug-
resistant fungi and biofilms are considered to be a global threat to human health due to the …

The increasing resistance of fungi to antibiotics is a severe challenge in public health, and
newly effective drugs are required. Promising potential medications are lipopeptides, linear …

Abstract Human α-defensin 5 (HD5) exhibits broad spectrum antimicrobial activity and plays
an important role in mucosal immunity of the small intestine. Although there have been …

Human α and β-defensins are cationic antimicrobial peptides characterized by three
disulfide bonds with a triple stranded β-sheet motif. It is presumed that interaction with the …

The concept of antimicrobial lipids as effectors of innate host defense is an emerging field.
There is limited knowledge on the antimicrobial role of lipids in the ocular environment …

As a family of cationic host defense peptides, human β-defensins (HBDs) are ubiquitous in
the oral cavity and are mainly synthesized primarily by epithelial cells, serving as the primary …